口腔扁平上皮癌の頸部リンパ節転移の超音波診断と偽陰性リンパ節の病理組織学的特徴

概要

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To contribute to early detection of occult lymph node metastasis, this retrospective study aimed to clarify the histopathological characteristics of false negative lymph node on ultrasonography. The results were as follows: 1) The area of metastasis within the false negative lymph nodes was significantly smaller than in the true positive lymph nodes, and in many cases tumor growth in a metastatic node was the infiltrative type. 2) Micrometastases occurred in twenty two of forty eight (45.8%) false negative lymph nodes and in these the metastatic area occupied less than 30%. 3) Twenty one of forty eight (43.8%) false negative lymph nodes had metastasis in an area of over 70%, and sixteen of these 21 had infiltrative growth type metastasis (76.2%). The false negative lymph nodes had more poorly differentiated type tumors than the true positive lymph nodes. These differences in histopathological characteristics affected both the results of the internal echo and the diagnosis regarding metastasis. 4) Concerning the relationship between mode of cancer invasion at the primary site and growth type in a metastatic node, mode 4 invasion at the primary site tended to have the infiltrative growth type.
札幌医科大学の論文
2003-04-01