<ORIGINAL ARTICLE>Localization of anti-monocyte/macrophage antibody-positive cells in periodontal tissue of rat maxillary molars after orthodontic tooth movement

概要

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To examine the localization of monoclonal anti-monocyte/macrophage (ED1) and macrophage (ED2) antibody-positive cells in periodontium, rat maxillary molar teeth were moved by insertion of band materials. The orthodontic tooth movement was elicited for 5 days, and paraffin-embedded maxillary teeth were stained by fluorescent immunocytochemistry and observed using a confocal laser scanning microscope. The localization of ED1-positive mononuclear cells in the experimental teeth was little different from that in the controls. While ED2-positive mononuclear cells were located throughout the periodontium on the distalside of controls, the number of positive cells decreased on the pressure side of the treated teeth. The present study suggested that most of the immunoreactive mononuclear cells on the distal side of controls are macrophages, while the positive cells on the pressure side of the experimental teeth are osteoclast precursors and a small number of macrophages.
北海道医療大学の論文
1997-12-30