<原著>Salivary duct carcinomaの免疫組織化学的研究 : 特に,多形性腺腫における腺管形成部との比較検討

概要

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The salivary duct carcinoma (SDC) is an extremely rare carcinoma arising from salivary glands and it is separate from adenocarcinomas in the new classification of salivary gland tumors by WHO in 1991. This study investigated the constituent cells in SDC by means of immunohistochemistry, and the results were compared with immunohistochemical studies of pleomorphic adenomas. We used anti-poly Keratin, AE-1, AE-3, vimentin, S-100, muscle actin, CEA, EMA, and SC as primary antibodies. The tumor cells in SDC were strongly positive for poly keratin, AE-1, and EMA. No myoepithelial cells were demonstrated within the tumor by negative staining of vimentin, S-100, and muscle actin. These results support the opinion that the SDC arises from the excretory duct of salivary glands or the inner layer of ductal structures in pleomorphic adenomas.
北海道医療大学の論文
1995-12-31