A Concept of Consensus Genic Sequence of tRNA Genes from Bacteria as a Key to Clarify Genetic Mechanisms

概要

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The first optimistic attempt was carried out to demonstrate usefulness of a concept of consensus genic sequence of tRNA, such as tRNAAla-tRNAMet-tRNAI1e/Met-tRNASer, from bacterih as a promising key to clarify the complicated genetic mechanisms such as transcription to RNAs and translation to proteins. First of all, bacttria were easily classified into five categories, Mycoplasmas, Gram-positive bacteria, Gram-negative bacteria, Archaebacteria and Bacteria of unknown categories. Then among genic sequences of tRNA and rRNA genes from bacteria, common genic sequences were intuitively searched for. The next, from the resultant common sequences, consensus sequences were subjectively chosen. Unexpectedly and luckily, resultant consensus sequences proved to be clearly related to their proper categories of bacteria without special intention. On the basis of the fact, categories of some of bacteria in Bacteria of unknown categories were on trial.
1995-01-31