<Abstract of Published Report>Highly Increased Cellular Accumulation of Vincristine, a Useful Hydrophobic Antitumor-drug, in Multidrug-resistant Solid Cancer Cells Induced by a Simply Reduced Taxinine.
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- Redcution of Uracil Derivatives with an NADH Model, 1-Benzyl-1,4-Dihydronicotinamide.
- Reactivity of Thioaldehyde : Cyclization Reaction of 6-Amino-1,3-dimethyl-5-thioformyluracil with Enamines into Pyrido[2,3-d]pyrimidine2,4-(1H, 3H)-diones.
- Highly Increased Cellular Accumulation of Vincristine, a Useful Hydrophobic Antitumor-drug, in Multidrug-resistant Solid Cancer Cells Induced by a Simply Reduced Taxinine.
- Convenient Methods for Regio- and/or Chemo-selective O-Deacylation of Taxinine, a Naturally Occurring Taxane Diterpenoid.
- Synthesis and Applications of [1-^N]-Labeled 4,6-Dimethyl-4H-[1,2,5]oxadiazolo[3,4-d]-pyrimidine-5,7-dione 1-Oxide as a Useful Tool for Mechanistic Investigations.
- Facile Synthesis and NO-Generating Property of 4H-[3,4-d]pyrimidine-5,7-dione 1-Oxides.
- Thermolysis of Taxinine and Taxinine H. : Allylic Reaarangement of the Ester Moiety in the C-Ring.
- Synthesess of Taxupine C Derivatives as Functiional Inhibitors of P-Glycoprotein, an ATP-Associated Cell-membrane Transporter.
- Facil Synthesis of a Novel Taxoid Closely Related to Bioactive Taxupine D. : Regio- and Stereo-selective Hydration of Taxinine, a Naturally Occurring Taxane Diterpenoid.
- Novel Synthesis of Purine Acyclonucleosides Possessing a Chiral 9-Hydroxyalkyl Group by Sugar Modification of 9-D-Ribitylpurines.
- Convenient Synthesis of Pyrido[4,3-d]pyrimidine-2,4(1H, 3H)-diones.
- A Convenient Synthesis of Acyclic Adenosines with an Unsaturated Side Chain by Modification of 9-(2,3-O-Isopropylidene-D-ribityl)adenine.
- Synthesis of 5-Arylthiouridines via Electrophilic Substitution of 5-Bromouridines with Diaryl Disulfides.
- Facil Method for the Preparation of 7-Methyl-8-oxoguanosines as an Immunomodulator.
- Thermolysis of Taxinine and Taxinine H. Allylic Rearrangement of the Ester Moiety in the C-Ring
- Syntheses of Taxuspine C Derivatives as Functional Inhibitors of P-Glycoprotein, an ATP-Associated Cell-Membrane Transporter
- A Novel Approach for the Synthesis of Purine Acyclonucleosides Using 9-D-Ribitylpurines as a Chiral Pool.
- Ribofuranose-ring Cleavage of Purine Nucleosides with Diisobutylaliminum Hydride : Convenient Method for the Preparation of Purine Acyclonucleosides.
- Facile Synthesis of a Novel Taxoid Closely Related to Bioactive Taxuspine D. Regio- and Stereo-Selective Hydration of Taxinine, a Naturally Occurring Taxane Diterpenoid
- Synthesis and DNA Photo-cleaving Activity of Novel Heterocyclic N-Oxide - Acridine Hybrid Molecules.
- Synthesis of Thymidine Derivatives 3'-Modified with a Polar Three-atom Group as Potential Anti-HIV-1 Agents.
- Facile Synthesis of 7,8-Dimethyl-10-D-ribitylpyrimido[5,4-b][1,4]benzothiazine-2,4(1H, 3H)-dione, a Deaza-thia Analog of 1,5-Dihydroriboflavin.
- A Newly Devised Method for the Debenzylation of N^6-Benzyladenosines. : A Convenient Synthesis of [6-N]-Labeled Adenosines.
- Synthesis of a Novel 5-Deaza-5-thia Analogue of Tetrahydrofolic Acid, N-(p-{[(2-Amino-6,7-dihydro-4-oxo-3H, 8H-pyrimido[5,4-b][1,4]thiazin-6-yl)methyl]amino}benzoyl)glutamic Acid.
- New and Facile Synthesis of 5,6,7,8-Tetrahydro-5-deaza-5-thiapterins via the Aliphatic S-N Type Smiles Rearrangement.
- Distinct Solvent-dependence in the Photoreactions of Purine Nucleosides with Pyrimido[5,4-g]pteridinetetrone N-Oxide : Possible Generation of Hydroxyl Radical from the Excited N-Oxide in Alcohols.
- Photoinduced Electron-Transfer Oxygenation of 7-Methyl-9-(β-D-ribofuranosyl)guaninium Salts : A prominent Effect of Iodide Anion
- Synthesis of a Ring-Scission Analogue of Neplanocin A as a Potential Inhibitor of S-Adenosylhomocysteine Hydrolase.
- Reductive Cleavage of the Ribose Moiety in Purine Nucleosides Using Diisobutylaluminum Hydride : A New Method for the Preparation of Acyclonucleosides.
- Diversity of Intramolecular Rearrangements of Uracil Derivatives to Pyrazolones and Hydantoins governed by a Prominent 5-Substituent Effect.
- Facile Synthesis of Thymidine Derivatives by Cross-Coupling of 5-Halogenouridine Derivatives with Trimethylaluminum.
- The Dimroth Rearrangement of 6-Aminouracil Derivatives.
- Oxidative Cyclization of 2', 3'-O-Isopropylideneadenosines into 5'-O, 8-Cycloadenosines with Lead Tetraacetate : Remarkable Effect of N^6-Substituents of the Oxidation.
- Convenient Method for the Synthesis of C-Alkylated Purine Nucleosides : Palladium-Catalyzed Cross-Coupling Reaction of Halogenopurine Nucleosides with Trialkylaluminums.