A Retinal 33kDa Protein is Recognized by Autoantibodies from Patients with Melanoma-associated Retinopathy
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概要
- 論文の詳細を見る
Previous studies revealed that sera of patients with cutaneous melanoma-associated retinopathy (MAR) specifically reacted with bipolar cells of the re-tina. However, the specific bipolar cell antigen has not yet been identified. To identify the bipolar cell MAR antigen, we performed an immunological in-vestigation using serum from MAR patients. In western blot analysis, retinal 33kDa protein was probed commonly with sera from MAR patients, while such immunoreactivity was not detected from patients with malignant melano-ma without retinopathy. This data strongly suggests that a novel retinal 33kDa protein may act as an autoantigen of MAR.
- 札幌医科大学の論文
著者
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Ohguro H
Department Of Ophthalmology Hirosaki University School Of Medicine
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Odagiri Hiroki
弘前大学 医学部外科
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OHGURO Hiroshi
Department of Ophthalmology and Visual Science, Sapporo Medical University School of Medicine
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Ohguro Hiroshi
Department Of Ophthalmology And Visual Science Sapporo Medical University School Of Medicine
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Ohguro Hiroshi
Department of Ophthalmology ,Sapporo Medical University School of Medicine
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