Associations of variations in the MRF2/ARID5B gene with susceptibility to type 2 diabetes in the Japanese population
スポンサーリンク
概要
- 論文の詳細を見る
- 2012-11-01
著者
-
Imai Yasushi
Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo
-
Imai Yasushi
Department Of Cardiovascular Medicine Graduate School Of Medicine The University Of Tokyo
-
Wang Guoqin
Department Of Cardiovascular Medicine The University Of Tokyo
-
Manabe Ichiro
Department Of Caldiology University Of Tokyo
-
Sugiyama Takao
Institute For Adult Disease Asahi Life Foundation
-
Maemura Koji
Department Of Cardiovascular Medicine Course Of Medical And Dental Sciences Graduate School Of Biome
-
Watanabe Masafumi
Department Of Cardiovascular Medicine Graduate School Of Medicine The University Of Tokyo
-
Itoh Chikako
Hiroshima A-bomb Casualty Council Health Management & Promotion Center
-
Hara Kazuo
Department Of Clinical Bioinformatics Graduate School Of Medicine University Of Tokyo
-
Yamazaki Tsutomu
Department Of Applied Chemistry Graduate School Of Engineering Tokyo University Of Agriculture And T
-
Nagai Ryozo
Department Cardiovascular Medicine The University Of Tokyo Hospital
-
Horikoshi Momoko
Department Of Metabolic Diseases Graduate School Of Medicine University Of Tokyo
-
Kadowaki Takashi
Department Of Cardiology Kawasaki Medical School
-
OZEKI Atsuko
Department of Cardiovascular Medicine, University of Tokyo Graduate School of Medicine
-
MANABE Ichiro
Department of Cardiovascular Medicine, Graduate School of Medicine, the University of Tokyo
-
MAEMURA Koji
Department of Cardiovascular Medicine, Graduate School of Medicine, the University of Tokyo
-
WATANABE Masafumi
Department of Cardiovascular Medicine, Graduate School of Medicine, the University of Tokyo
-
OZEKI Atsuko
Department of Cardiovascular Medicine, Graduate School of Medicine, the University of Tokyo
-
HORIKOSHI Momoko
Department of Diabetes and Metabolism, Graduate School of Medicine, the University of Tokyo
-
WANG Guoqin
Department of Cardiovascular Medicine, Graduate School of Medicine, the University of Tokyo
-
HORIKOSHI Momoko
Department of Diabetes and Metabolic Diseases, Graduate School of Medicine, The University of Tokyo
関連論文
- Successful Catheter Ablation of Atrial Tachycardia and Atrial Fibrillation in Persistent Left Superior Vena Cava
- A Case of Neonatal Lupus Erythematosus Presenting Delayed Dilated Cardiomyopathy With Circulating Autoantibody to Annexin A6
- OJ-217 Genetic Variations of Mrf-2/Arid5B Confers Risk of Coronary Atherosclerosis in the Japanese Population(Genetics/Genetically engineered models/Gene therapy-2(H/M), The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- Adipose Tissue Remodeling and Malfunctioning in Obesity Revealed by in vivo Molecular Imaging
- PJ-482 The Polymorphism in the Adiponectin Gene is Associated with Susceptibility to Coronary Artery Disease(Atherosclerosis, clinical-11 (H) PJ81,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society
- PE-145 The Clinical Application of the Pharmacogenomics for Optimizing Warfarin Dosage(PE025,Thromboembolism/Antithrombotic Therapy/Thrombolysis 2 (IHD),Poster Session (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- ATP binding Cassette Transporter (ABCA1) variant is one of the determinantsof plasma high density lipoprotein level in Japanese population
- Evidence for association of Ser326Cys polymorphism in 8-oxyguanin DNA glycosylase (OGG1) with susceptibility to coronary heart disease in Japanese
- The Matrix Metalloproteinase-1 (MMP-1) 1G/2G Polymorphism and the Matrix Metalloproteinase-3 (MMP-3) 5A/6A Polymorphism are Useful Genetic Markers for Myocardial Infarction
- Peripheral Biological Clocks Exist in Cultured Cardiomyocytes
- Cultured Vascular Endothelial Cells Show Circadian Oscillation of Clock Related Genes
- Angiotensin II stimulation induces TGF β and its related proteins in cardiac fibroblasts
- Establishment of clinical data management system and its practical application to genetic epidemiology in cardiovascular medicine
- Development of a Pioneering Clinical Support System Utilizing Information Technology : Clinical Informatics and Genome Analysis
- Genetic Variations of Mrf-2/Arid5b Confer Risk of Coronary Atherosclerosis in the Japanese Population
- PE-566 Variations in the Origins of Mature Smooth Muscle Cells with SM1/2 Expression in Vascular Remodeling(Development and differentiation-3 (M) PE97,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Soci
- PE-320 Synthetic Retinoid (Am80) Suppresses Smooth Muscle Phenotypic Modulation and Neointima Formaion by Disrupting a Transcriptional Complex of KLF5/RAR/RXR(Vascular smooth muscles-2 (H) PE54,Poster Session (English),The 70th Anniversary Annual Scientif
- Genetic Analysis in a Patient With Recurrent Cardiac Myxoma and Endocrinopathy
- Relationship Between Renal Dysfunction and Severity of Coronary Artery Disease in Japanese Patients
- PJ-038 Cystatin C Predicts Severity of Coronary Artery Disease Even in Patients without Chronic Kidney Disease (CKD)(PJ007,Kidney/Renal Circulation/CKD 1 (H),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- FRS-060 SUMOylation of KLF5 is a key molecular switch of transcriptional regulatory programs of lipid metabolism(New Insights into Metabolic Syndrome(02)(H),Featured Research Session,The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- Association of TCF7L2 polymorphisms with susceptibility to type 2 diabetes in 4,087 Japanese subjects
- PE-537 Identification of the Novel MEF2-Kruppel-like Factor 5 (KLF5) Network That Associates with Cardiovascular Disease(Molecular biology, vascular-3, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- PE-411 KLF5 Controls Metabolic Stress Response in Metabolic Syndrome and Cardiovascular Disease(Diabetes/Obesity/Metabolic syndrome-05, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- OE-233 Angiotensin II and Free Cholesterol Synergistically Impaired eNOS Biolavailability via Intracellular Raft-like Domain(OE40,Atherosclerosis, Basic 2 (IHD),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Soc
- PJ-409 Angiotensin II and Cholesterol Synergistically Induce Endothelial Dysfunction by eNOS Trafficking(Atherosclerosis, basic(07)(IHD),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- OE-174 Molecular Mechanism of Soluble Form of VEGFR-1 (sVEGFR-1)Expression in Vascular Endothelial Cell(Molecular biology, vascular(01)(IHD),Oral Presentation(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- OE-044 Long Pentraxin 3 (PTX3) is More Specific than C-reactive Protein (CRP) as a Marker for Vascular Inflammation(Atherosclerosis, clinical-01, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- OE-019 Peripheral Clock Regulates Circadian Thrombomodulin Gene Expression in Vascular Endothelial Cells(Molecular biology, vascular-1 (H) OE4,Oral Presentation (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- The Significant Association of Genetic Polymorphisms in the KLF5 Gene with Coronary Artery Disease(Atherosclerosis, Clinical 9 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Resistin Induces Adhesion Molecules through NF-κB Pathway in Vascular Endothelial Cells(Infection/Inflammation/Immunity 2 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Resistin Inhibits Endothelial Cell Migration and Angiogenesis(Metabolic Syndrome (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Hypoxia Inducible Factor Mediates Angiotensin II-Induced Cardiac Hypertrophy(Renin-angiotensin-aldosterone System (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-447 The genetic polymorphisms in the insulin-resistance related genes as coronary risks(Preventive Medicine/Epidemiology/Education 4 (H) : PJ75)(Poster Session (Japanese))
- OJ-171 CRP Induces PAI-1 Gene Expression through Tyrosine Kinase and NF-κB Signaling Pathways(Infection/Inflammation/Immunity 1 (H) : OJ20)(Oral Presentation (Japanese))
- OJ-168 Kruppel-like zinc-finger trascription factor 5 (KLF5) madiate immune responses in cardiovascular remodeling(Infection/Inflammation/Immunity 1 (H) : OJ20)(Oral Presentation (Japanese))
- Carvedilol Therapy Improved Left Ventricular Function in a Patient With Arrhythmogenic Right Ventricular Cardiomyopathy
- Kruppel-Like Zinc-Finger Transcription Factor KLF5/BTEB2 ls a Target for Angiotensin II Signaling and an Essential Regulator of Cardiovascular Remodeling.
- Obese adipose tissue remodeling, malfunctioning, and chronic inflammation visualized by in vivo molecular imaging
- PJ-178 Free Fatty Acid, Palmitate, Induces Metabolic and Vascular Lipotoxicity via the IRE1 Arm of ER Stress Response Pathways(PJ030,Metabolic Syndrome 1 (H),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- Altered Manganese Superoxide Dismutase Activity Resulting from Alanine/Valine Polymorphism Affects the Apoptosis of Macrophages Causude by Oxidized Low Density Lipoprotein(Apoptosis/Necrosis/Regeneration 1 (M), The 69th Annual Scientific Meeting of the Ja
- 4 Bone marrow-derived cells contribute to vascular wall inflammation without differentiating into smooth muscle cells(Young Investigator's Award Finalists Lectures (YIA),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- PE-343 Novel Regulatory Pathway of PDGF-A Chain as Mediated by Transcription Factor KLF5 through Cooperative Activation with NF-κB and Phorbol Ester(Molecular Biology, Vascular 3 (H) : PE59)(Poster Session (English))
- OE-102 Positive and negative regulation of the cardiovascular transcription factor KLF5 by p300 and SET through interaction and acetylation(Molecular Biology, Vascular 1 (H) : OE12)(Oral Presentation (English))
- Proteomic Identification of a Transcriptional Represser of the Transcription Factor KLF5/BTEB2
- KLF5 not only Synergistically Activates PDGF-A Gene with NFκ B but also Accelerates SMC Proliferation
- Angiotensin II downregulates renal expression of anti-aging gene, kiotho, and exogenous klotho gene transfer ameliorates angiotensin II-induced renal damage
- DPE-071 Retinoic Acid Receptor Antagonist Ameliorates Pressure Overload-Induced Cardiac Hypertrophy and Remodeling(DPE12,Cardiomyopathy/Hypertrophy (Basic) (M),Digital Poster Session (English),The 73rd Annual Scientific Meeting of The Japanese Circulation
- OE-057 Saturated Fatty Acid, Palmitate, Promotes Smooth Muscle Phenotypic Modulation and Exacerbates Neointima Formation(OE10,Atherosclerosis, Basic 1 (IHD),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society
- FRS-104 KLF5 Controls Tissue Remodeling in Cardiovascular and Kidney Diseases via S100 Proteins(FRS21,New Insights into Chronic Kidney Disease and Renal Circulation (H),Featured Research Session (English),The 73rd Annual Scientific Meeting of The Japanese
- FRS-093 Significance of the Transcription Factor KLF5 in Myocardial Hypertrophy in Response to Pressure Overload(FRS19,Genetic Abnormalities in Cardiac Hypertrophy and Cardiomyopathy (M),Featured Research Session (English),The 73rd Annual Scientific Meeti
- FRS-079 Rad51 Plays a Pivotal Role in Adipose Tissue Obesity and Systemic Insulin Resistance(FRS16,Basic Mechanisms of Lipid Disorders and Metabolic Syndrome (H),Featured Research Session (English),The 73rd Annual Scientific Meeting of The Japanese Circul
- Reduced Adiponectin Level Is Associated With Severity of Coronary Artery Disease
- Manganese Superoxide Dismutase (MnSOD) Alanine-to-Valine Polymorphism Is Associated with Coronary Artery Disease
- Genetic variants in the calpain-10 gene and the development of type 2 diabetes in the Japanese population
- OE-054 Quality of Life Provides Additional Prognostic Information in Heart Failure Outpatients : A Two-year Follow-up Study(OE09,Heart Failure (Treatment) 1 (M),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Soc
- OE-301 Direct Reciprocal Effect of Resistin and Adiponectin on Vascular Endothelial Cells(Endothelium/NO 4 (H) : OE38)(Oral Presentation (English))
- OE-009 Delivery of Endothelial PAS Domain Protein1 Gene Promotes Angiogenesis through the Transactivation of Both VEGF and Its Receptor, Flt-1(Vasoactive Compound/Growth Factor/Cytokine 1 (H) : OE2)(Oral Presentation (English))
- Angiotensin II Type I Receptor Antagonist Prevents Renal Damage in Aged Transgenic Mice Overexpressing Endothelin-1
- Insulin Receptor Substrate Deficient Mice Demonstrates Elevated Blood Pressure and Endothelial Cell Dysfunction
- Delivery of Endothelial PAS Domain Protein1 Gene Promotes Anglogenesis through the Transactivation of Both VEGF and Its Receptor, Flt-1
- The Significant Association of the Genetic Polymorphisms of Werner Helicase and β2 Adrenergic Receptor with Susceptibility to Coronary Heart Disease
- Microalbuminuria Reduction with Telmisartan in Normotensive and Hypertensive Japanese Patients with Type 2 Diabetes : A Post-Hoc Analysis of the Incipient to Overt : Angiotensin II Blocker, Telmisartan, Investigation on Type 2 Diabetic Nephropathy (INNOVA
- Antibody-mediated Insulin Resistance Treated by Cessation of Insulin Administration
- Establishment of a method of anonymization of DNA samples in genetic research
- An E-Box Binding Transcription Factor Controls Smooth Muscle Cell Differentiation Marker Genes
- Kruppel Like Zinc-Finger Trascription Factor 5 (KLF5) Madiate Immune Responses in Cardiovascular Remodeling
- Mechanisms of maintenance of endothelial function by the aging-suppressor gene Klotho
- Adrenomedullin activates the protein kinase Akt in endothelial cells
- A novel pathway involving the mitogen Trichostatin A and the transcription factor IKLF/BTEB2 in regulation of the SMemb gene
- TAF-1 is a transcriptional cofactor that represses activation by the transcription factor IKLF/BTEB2
- PDGF-A chain is regulated by the transcription factor IKLF/BTEB2
- Transcriptional activation by acetylation of the transcription factor IKLF/BTEB2 by p300
- p300 activates transcription by the transcription factor IKLF/BTEB2 -implications for a role in cell-cycle arrest and differentiation
- Targeted inhibition of the transcription factor IKLF / BTEB2 results in growth arrest of smooth muscle cells
- 5 Establishment of clinical database system and identification of genetic factors contributing to the pathogenesis of atheroscherosis(Symposium 4 (SY4) (IHD) : Molecular Mechanism of Atherosclerosis)(Special Program)
- Proteinases Including MMPs Are Involved in the Pathogenesis of Aortic Aneurysm : A Study of the Transcription Profile with DMA Microarray
- Insulin Receptor Substrate Deficient Mice Serve as Animal Models of Endothelial Cell Dysfunction due to Insulin Resistance
- Plasma Cystatin C Concentration Reflects the Severity of Coronary Artery Disease in Patients Without Chronic Kidney Disease
- Endothelial PAS Domain Protein 1 (EPAS1) Regulates the Fit-1 Gene Expression in Hypoxia
- Association between single nucleotide polymorphisms within genes encoding sirtuin families and diabetic nephropathy in Japanese subjects with type 2 diabetes
- Report of the Committee on the classification and diagnostic criteria of diabetes mellitus : The Committee of the Japan Diabetes Society on the diagnostic criteria of diabetes mellitus
- Japan Prevention Trial of Diabetes by Pitavastatin in Patients with Impaired Glucose Tolerance (the J-PREDICT study) : rationale, study design, and clinical characteristics of 1269 patients
- Idiopathic retroperitoneal fibrosis, inflammatory aortic aneurysm, and inflammatory pericarditis-Retrospective analysis of 11 case histories
- Multifocal fibrosclerosis and IgG4-related disease involving the cardiovascular system
- Associations of variations in the MRF2/ARID5B gene with susceptibility to type 2 diabetes in the Japanese population
- Intrathoracic Impedance Monitoring in Patients With Heart Failure
- Construction of a prediction model for type 2 diabetes mellitus in the Japanese population based on 11 genes with strong evidence of the association
- Intrathoracic Impedance Monitoring in Patients With Heart Failure : Correlation With Dehydration and Bleeding Events
- Early decision for a left ventricular assist device implantation is necessary for patients with modifier A
- Anti-arrhythmic device therapy has limits in improving the prognosis of patients with cardiac amyloidosis
- The Clinical Efficacy of Novel Vectorcardiographic Descriptors of Ventricular Electrical Activation Digitally Converted from Standard 12-Lead Electrocardiogram
- Urgent Management of Rapid Heart Rate in Patients With Atrial Fibrillation/Flutter and Left Ventricular Dysfunction:– Comparison of the Ultra-Short-Acting β1-Selective Blocker Landiolol With Digoxin (J-Land Study) –
- Circulating Transforming Growth Factor β-1 Level in Japanese Patients With Marfan Syndrome
- Radiofrequency Catheter Ablation of the Accessory Pathway Adversely Affected the Left Ventricular Outflow Tract Pressure Gradient in a Patient With Hypertrophic Obstructive Cardiomyopathy
- Associations of variations in the MRF2/ARID5B gene with susceptibility to type 2 diabetes in the Japanese population
- Supraventricular Tachycardia Originating From the Posterior Atrioventricular Node in the Univentricular Heart With Single Atrium
- Subarachnoid Hemorrhage from Mycotic Aneurysms
- Urgent Management of Rapid Heart Rate in Patients With Atrial Fibrillation/Flutter and Left Ventricular Dysfunction : Comparison of the Ultra-Short-Acting β1-Selective Blocker Landiolol With Digoxin (J-Land Study)