Concurrent presentation of cryptococcal meningoencephalitis and systemic lupus erythematosus

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概要

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• Cryptococcal meningitis is a recognized complication of systemic lupus erythematosus (SLE), with high mortality rates, particularly in those treated with immunosuppressive agents. We describe a patient diagnosed simultaneously with cryptococcal meningoencephalitis and SLE and reviewed four similar cases reported in the literature. In our case, profound low CD4 lymphocyte count and low complement levels were observed. The patient was treated with prednisolone, fluconazole, and 5-flucytosine and evinced good clinical improvement. This case suggests that intrinsic immunological abnormality related to SLE predisposed to opportunistic infections. © 2010 Japan College of Rheumatology.

• 2011-06-01

著者

• Yamagishi Masakazu

  Division of Cardiovascular Medicine, Kanazawa University Graduate School of Medical Science

• Yamagishi Masakazu

  Division Of Cardiovascular Medicine Kanazawa University Graduate School Of Medical Science

• Yamagishi Masakazu

  Division Of Rheumatology Department Of Internal Medicine Graduate School Of Medical Science Kanazawa

• Yamada Kazunori

  Division Of Cardiology Shizuoka City Hospital

• Matsumura Masami

  Division Of Rheumatology Department Of Internal Medicine Graduate School Of Medical Science Kanazawa

• Kawano Mitsuhiro

  Division Of Rheumatology Department Of Internal Medicine Graduate School Of Medical Science Kanazawa

• Kawano Mitsuhiro

  Division Of Rheumatology Kanazawa University Graduate School Of Medical Science

• Inoue Ryo

  Division Of Nephrology And Rheumatology Ishikawa Prefectural Central Hospital

• Yamada Kazunori

  Division Of Rheumatology Department Of Internal Medicine Graduate School Of Medical Science Kanazawa

• Yamagishi Masakazu

  Division Of Cardiology Department Of Internal Medicine Kanazawa University Graduate School Of Medici

• MATSUMURA Masami

  Research Center for Medical Education, Kanazawa University Graduate School of Medicine

• KAWAMURA Rika

  Division of Rheumatology, Department of Internal Medicine, Kanazawa University Graduate School of Me

• Kawamura Rika

  Division Of Rheumatology Department Of Internal Medicine Kanazawa University Graduate School Of Medi

• Matsumura Masami

  Research Center For Medical Education Kanazawa University Graduate School Of Medicine

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