Cell Size Regulation during Telomere-Directed Senescence in Saccharomyces cerevisiae
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概要
- 論文の詳細を見る
DNA replication without telomerase leads to telomere shortening and induces replicative senescence. We found that in a telomerase-deficient budding yeast mutant, the volume of each telomere-shortened cell increased as its growth capacity decreased, and that this process was associated with changes in vacuolar morphology. Senescence-induced cell expansion required Mec1, a DNA damage-responsive kinase, but not vacuolar SNARE Vam3.
- 社団法人 日本農芸化学会の論文
- 2010-01-23
著者
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Matsuura Akira
Dep. Of Biology Fac. Of Sci. Chiba Univ.
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Matsuura Akira
Department Of Biology Faculty Of Science Chiba University
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MATSUI Aiko
Department of Nanobiology, Graduate School of Advanced Integration Science, Chiba University
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Matsui Aiko
Department Of Nanobiology Graduate School Of Advanced Integration Science Chiba University
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