Visualization of Aberrant Perinuclear Microtubule Aster Organization by Microtubule-Destabilizing Agents
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概要
- 論文の詳細を見る
To analyze aberrant spindle formation by microtubule-targeting drugs, live cell imaging was performed using multi-fluorescent human MDA-MB-435 cells in which several spindle components were visualized. Time-lapse images revealed that nocodazole and vinblastine induced additional perinuclear asters at the onset of mitosis. These results imply that these drugs stimulate the microtubule-organizing activity, despite their microtubule-destabilizing properties.
- 社団法人 日本農芸化学会の論文
- 2009-05-23
著者
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SUGIMOTO KENJI
Laboratory of Applied Molecular Biology, Division of Applied Biochemistry, Graduate School of Agricu
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Sugimoto Kenji
Laboratory Of Applied Molecular Biology Division Of Applied Biochemistry Graduate School Of Agricult
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SAKAUSHI Shinji
Laboratory of Molecular Biology and Cell Informatics, Division of Bioscience and Informatics, Gradua
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SENDA-MURATA Kaori
Laboratory of Molecular Biology and Cell Informatics, Division of Bioscience and Informatics, Gradua
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OKA Shigenori
Laboratory of Molecular Biology and Cell Informatics, Division of Bioscience and Informatics, Gradua
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Oka Shigenori
Laboratory Of Molecular Biology And Cell Informatics Graduate School Of Life And Environmental Scien
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Sugimoto Kenji
Laboratory Of Molecular Biology And Cell Informatics Graduate School Of Life And Environmental Scien
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SENDA MURATA
Laboratory of Molecular Biology and Cell Informatics, Graduate School of Life and Environmental Scie
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Senda Murata
Laboratory Of Molecular Biology And Cell Informatics Graduate School Of Life And Environmental Scien
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Sakaushi Shinji
Laboratory Of Molecular Biology And Cell Informatics Graduate School Of Life And Environmental Scien
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Sugimoto Kenji
Laboratory Of Applied Molecular Biology Department Of Applied Biochemistry Osaka Prefecture Universi
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Sugimoto Kenji
Laboratory Of Molecular Biology And Cell Informatics Division Of Bioscience And Informatics Graduate
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Senda Murata
Laboratory Of Molecular Biology And Cell Informatics Division Of Bioscience And Informatics Graduate School Of Life And Environmental Sciences Osaka Prefecture University
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