子宮内膜の炎症がラットの発情周期におよぼす影響
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概要
- 論文の詳細を見る
To investigate how uterine inflammation affects ovarian activity in rats, endometritis was induced and changes in the length of estrous cycle and serum concentrations of estradiol-17β (E2) and progesterone (P4) were examined. A suspension of Staphylococcus aureus (bacterial solution) or iodine solution was infused into the uterine lumen at various estrous phases. When the bacterial solution was infused at estrus, metestrus, or the first day of diestrus, the following diestrus continued for 5 to 12 days. In the case of the iodine solution, regardless of the estrous phase of the infusion, the following diestrus continued for approximately 6 days. E2 concentration after infusion of each solution did not fluctuate largely and remained at a low concentration (around 5 pg/ml). P4 concentration was high (35-45 ng/ml) on the day following infusion, but decreased rapidly to base line values within a few days and remained thereafter at a low level (around 5 ng/ml). It is assumed that the endometritis caused by biological or chemical stimulation raises the concentration of P4 to depress gonadotrophic hormone secretion, and hence this high P4 concentration might inhibit the growth of ovarian follicles.
- 日本繁殖生物学会の論文
- 2004-06-01
著者
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Furuichi Tomohiro
Department of Cardiology, Surugadai Nihon University Hospital
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Aoki Hajime
Department of Cardiology, Yokohama Rosai Hospital
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Aoki H
Department Of Physics Saga University
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Kawakami Shizuo
Department Of Theriogenology Azabu University
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Furuichi T
Department Of Veterinary Obstetrics And Gynecology School Of Veterinary Medicine Azabu University
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Kaneko K
Department Of Veterinary Obstetrics And Gynecology School Of Veterinary Medicine Azabu University
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Kaneko Kazuyuki
Department Of Orthodontics And Dentofacial Orthopedics The University Of Tokushima Graduate School O
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Kawakami S
Department Of Veterinary Obstetrics And Gynecology School Of Veterinary Medicine Azabu University
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AOKI Hajime
Veterinary Clinical Center
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HATORI Sachiko
Department of Veterinary Obstetrics and Gynecology, School of Veterinary Medicine, Azabu University
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TANIMOTO Hanako
Department of Veterinary Obstetrics and Gynecology, School of Veterinary Medicine, Azabu University
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AOKI Hajime
High Energy Accelerator Research Organization, KEK
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Hatori Sachiko
Department Of Veterinary Obstetrics And Gynecology School Of Veterinary Medicine Azabu University
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Tanimoto Hanako
Department Of Veterinary Obstetrics And Gynecology School Of Veterinary Medicine Azabu University
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AOKI Hajime
Department of Physics, University of Tokyo
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金子 一幸
Department of Veterinary Obstetrics and Gynecology, School of Veterinary Medicine, Azabu University
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青木 創
Department of Veterinary Obstetrics and Gynecology, School of Veterinary Medicine, Azabu University
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古市 朋大
Department of Veterinary Obstetrics and Gynecology, School of Veterinary Medicine, Azabu University
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