Cellular and Molecular Mechanisms of Immuno-modulation by Ganoderma lucidum
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概要
- 論文の詳細を見る
Ganoderma lucidum (Leyss. ex Fr.) Karst. (Lingzhi or Reishi) has been used for a long time in China to prevent and treat various human diseases. G. lucidum polysaccharides extracted from G. lucidum are one of efficacious ingredient groups of G. lucidum. A number of reports have demonstrated that G. lucidum polysaccharides modulate immune function both in vivo and in vitro. The immuno-modulating effects of G. lucidum polysaccharides were extensive, including promoting the function of antigen-presenting cells, mononuclear phygocyte system, humoral immunity, and cellular immunity. Cellular and molecular mechanisms, possible receptors involved, and triggered signaling cascades have also been studied in vitro. However, whole animal experiments are still needed to further establish the mechanism of the immuno-modulating effects by G. lucidum. Evidence-based clinical trials are also needed.
- 社団法人 日本薬理学会の論文
- 2005-10-20
著者
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LIN Zhi-Bin
Department of Pharmacology, Basic Medical School, Beijing (Peking) University
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Lin Zhi-bin
中華人民共和国
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Lin Zhi-bin
Department Of Pharmacology Basic Medical School Beijing (peking) University
関連論文
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- Cellular and Molecular Mechanisms of Immuno-modulation by Ganoderma lucidum
- Polysaccharide Extract Isolated From Ganoderma lucidum Protects Rat Cerebral Cortical Neurons From Hypoxia/Reoxygenation Injury
- Response of human dendritic cells to different immunomodulatory polysaccharides derived from mushroom and barley
- Polysaccharide Extract Isolated From Ganoderma lucidum Protects Rat Cerebral Cortical Neurons From Hypoxia/Reoxygenation Injury