Emetic Responses and Neural Activity in Young Musk Shrews during the Breast-Feeding/Weaning Period : Comparison between the High and Low Emetic Response Strains Using a Shaking Stimulus
スポンサーリンク
概要
- 論文の詳細を見る
The high emetic response (HER) strain and low emetic response (LER) strain of musk shrews (Suncus murinus) markedly differ in the emetic reflex in adults. However, there have been no studies on young musk shrews. We gave a shaking stimulus to young musk shrews aged 10 days or more that were obtained by mating within each strain and observed emetic responses. In the HER strain, no animal aged 10 days vomited, but vomiting was observed in 1 of 5 animals each aged 12 and 14 days, 2 of 5 animals aged 16 days, and all animals aged 18 days or more. In the LER strain, no vomiting was observed until the age of 14 days, but at the age of 16 days or more, 1 or 2 of 5 animals at each age vomited. After stimulation, activated neurons of the dorsal vagal complex and the dorsal reticular formation of the nucleus ambiguus (Amb) were examined by Fos immunohistochemistry. This morphometric study demonstrated that the numbers of Fos-positive neurons in the nucleus of the solitary tract and the dorsal reticular formation of the Amb were significantly larger in the animals that vomited in the HER strain than animals that did not vomit in the LER strain. We suggest that neurons in these regions are involved in emetic responses, as is the case in adult animals.
- 社団法人 日本実験動物学会の論文
著者
-
Ebukuro S
Central Inst. Experimental Animals Kanagawa Jpn
-
Ebukuro Susumu
Animal Resource Center Central Institute For Experimental Animals
-
MAEDA Seishi
Department of Anatomy, Hyogo College of Medicine
-
SEKI MAKOTO
Department of Gastrointestinal Surgery, Cancer Institute Hospital
-
Seki M
Department Of Anatomy Hyogo College Of Medicine
-
Seki Makoto
Department Of Environmental Biology And Chemistry Faculty Of Science
-
Ito H
The Institute Of Experimental Animal Sciences Hyogo College Of Medicine
-
ITO Hisao
The Institute of Experimental Animal Sciences, Hyogo College of Medicine
-
NISHIBAYASHI Mitsuru
The Institute of Experimental Animal Sciences, Hyogo College of Medicine
-
Ito Hisao
The Institute Of Experimental Animal Sciences Hyogo College Of Medicine
-
Nishibayashi Mitsuru
The Institute Of Experimental Animal Sciences
-
Maeda Seishi
Department Of Anatomy Hyogo College Of Medicine
-
Seki Makoto
Department of 1st Anatomy, Hyogo College of Medicine
-
Maeda Seishi
Department of 1st Anatomy, Hyogo College of Medicine
-
ITO Hisao
The Institute of Experimental Animal Center, Hyogo College of Medicine
関連論文
- Immunohistochemical Localization of Aquaporin-4 in the Rat Pituitary Gland
- マウス精巣におけるプリオン遺伝子mRNA発現パターンについて
- Sedative Effect of Medetomidine and its Reversal by Atipamezole in House Musk Shrews (Suncus murinus)
- Extended Left Hepatectomy by Severing All Major Hepatic Veins with Reconstruction of the Right Hepatic Vein
- Surgery for multiple hepatic colorectal metastases
- "P-76 Effects of Food Restriction on Repeated Doses of Carbon Tetrachloride Toxicity in Rats.
- Effect of feed restriction in long term caged rats
- Characterization of Cytoplasmic Dynein Light-intermediate Chain isoforms in Rat Testis
- Localization of Cytoplasmic Dynein Light-intermediate Chain mRNA in the Rat Testis Using In Situ Hybridization
- Emetic Responses and Neural Activity in Young Musk Shrews during the Breast-Feeding/Weaning Period : Comparison between the High and Low Emetic Response Strains Using a Shaking Stimulus
- Apoptosis and retinal projections in the dorsal lateral geniculate nucleus after monocular deprivation during the later phase of the critical period in the rat
- Immunohistochemical Demonstration of c-fos Protein in Neurons of the Medulla Oblongata of the Musk Shrew (Suncus murinus) after Veratrine Administration
- A Parasympathetic Ganglion Innervating the Harderian Gland and Lacrimal Gland of the Musk Shrew (Suncus murinus): Fluorescent Tracing and Immunohistochemical Studies
- Transcatheter arterial infusion chemotherapy with cisplatin-lipiodol suspension in patients with hepatocellular carcinoma
- Hepatic parenchymal transection using ultrasonic coagulating shears : a preliminary report
- OBSEVATION OF CILIARY EFFECTIVE STROKE REACTIVATED IN THE PRESENCE OF VANADATE(Cell Biology and Morphology,Abstracts of papers presented at the 76^ Annual Meeting of the Zoological Society of Japan)
- 解剖学:ラット下垂体におけるアクアポリンの発現
- マウス精巣におけるプリオン遺伝子mRNA発現パターンについて
- Subnuclear distribution of afferents from the oral, pharyngeal and laryngeal regions in the nucleus tractus solitarii of the rat : a study using transganglionic transport of cholera toxin
- ラットセルトリ細胞における微小管関連モータータンパク質の局在
- Clinicopathology of pancreaticobiliary maljunction : relationship between alterations in background biliary epithelium and neoplastic development
- Extrapancreatic tumours in 9 cases : Differential diagnosis from primary pancreatic tumors with marked extrapancreatic growth based on imaging studies
- Pancreatic endocrine tumor : Pancreatographic features
- Surgical treatment of intraductal papillary-mucinous tumor (IPMT) of the pancreas : operative indications based on surgico-pathologic study focusing on invasive carcinoma derived from IPMT
- EFFECTS OF FOOD RESTRICTION ON REPRODUCTIVE AND TOXICOLOGICAL PARAMETERS IN RATS : IN SEARCH OF SUITABLE FEEDING REGIMEN IN LONG-TERM TESTS
- EFFECT OF FOOD RESTRICTION ON HEPATOTOXICITY OF CARBON TETRACHLORIDE IN RATS
- PHOSPHODIESTERASE IN THE CILIARY CONTROL OF PARAMECIUM(Cell Biology and Morphology,Abstracts of papers presented at the 75^ Annual Meeting of the Zoological Society of Japan)
- Localization of Aquaporin Water Channels in the Airway of the Musk Shrew (Suncus murinus) and the Rat
- Mesenteric fibromatosis of the transverse colon with the reconstruction of the superior mesenteric arteries : report of a case
- Systemic Administration of Lipopolysaccharide Increases the Expression of Aquaporin-4 in the Rat Anterior Pituitary Gland
- Expression of Adrenergic and Cholinergic Receptors in Murine Renal Intercalated Cells