Cardiovascular Risk Factors in Hemodialysis Patients : Results from Baseline Data of Kaleidoscopic Approaches to Patients with End-stage Renal Disease Study
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概要
- 論文の詳細を見る
BACKGROUND: The prevalence of cardiovascular risk factors and the prevalence of comorbidities in adult hemodialysis patients in Japan are not fully understood.METHODS: In "Kaleidoscopic Approaches to Patients with End-stage Renal Disease Study" (The KAREN Study, 2003), trained research stuff examined 1,214 adult hemodialysis patients (mean age, 61.2 years; 779 males and 435 females) of 1,506 patients in northern areas of Iwate Prefecture. Cardiovascular risk factors and the prevalence of comorbidities in hemodialysis patients were compared with those in the general population using direct age-adjustment methodology and standardized morbidity ratios (SMRs).RESULTS: In hemodialysis patients, common causes of end-stage renal disease were chronic glomerulonephritis (29.8%), diabetic nephropathy (24.5%), and other diseases. Prevalence and SMR of myocardial infarction were 5% and 9.6, respectively, and those of stroke were 13% and 5.7. The prevalences of hypertension and diabetes mellitus were 87% and 29%, respectively. Mean systolic blood pressure and mean diastolic blood pressure were 155 mmHg and 85 mmHg, respectively. Mean levels of total serum cholesterol, high-density lipoprotein cholesterol, and albumin in patients with end-stage renal disease were lower than those of the general population (160.6 vs. 203.3 mg/dL, 48.5 vs. 59.7 mg/dL, and 3.7 vs. 4.4 g/dL, respectively). Mean levels of C-reactive protein were higher than those of the general population (3.80 vs. 1.16 mg/L).CONCLUSION: Hemodialysis patients have a high prevalence of cardiovascular risk factors and comorbidities. Levels of nutrition-related markers were lower, and C-reactive protein levels were higher, in hemodialysis patients than in the general population.J Epidemiol 2005 ;15: 96-105.
- 日本疫学会の論文
- 2005-05-01
著者
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OHSAWA Masaki
Department of Hygiene and Preventive Medicine, Iwate Medical University
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KATO Karen
Department of Urology, Iwate Medical University
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ITAI Kazuyoshi
Department of Hygiene and Preventive Medicine, Iwate Medical University
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KONDA Ryuichiro
Department of Urology, Iwate Medical University
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ONODA Toshiyuki
Department of Hygiene and Preventive Medicine, Iwate Medical University
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FUJIOKA Tomoaki
Department of Urology, Iwate Medical University
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Nakamura Motoyuki
Division Of Cardiology Department Of Internal Medicine And Memorial Heart Center Iwate Medical Unive
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Fujioka Tomoaki
Department Of Urology Iwate Medical University
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NAKAMURA Motoyuki
Second Department of Internal Medicine, School of Medicine, Iwate Medical University
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OKAYAMA Akira
Department of Preventive Cardiology, National Cardiovascular Center
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Nakamura Motoyuki
岩手医科大学 内科学講座循環器内科
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Ohsawa Masaki
Department Of Hygiene And Preventive Medicine Iwate Medical University
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Kato Karen
Department Of Urology Iwate Medical University
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Okayama Akira
Department Of Orthopedic Surgery Hyogo College Of Medicine
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Itai Kazuyoshi
Department Of Hygiene And Preventive Medicine Iwate Medical University
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Nakamura Motoyuki
Second Department Of Medicine Iwate Medical University
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Ojima Toshiyuki
Department Of Hygiene And Preventive Medicine Iwate Medical University
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Konda Ryuichiro
Department Of Urology Iwate Medical University
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Tanaka Fumitaka
Department Of Internal Medicine (cardiology Division) Iwate Medical University
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Onoda Toshiyuki
Department Of Hygiene And Preventive Medicine Iwate Medical University
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Okayama Akira
Department Of Hygiene And Preventive Medicine Osaka University School Of Medicine Nakanoshima
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Nakamura Motoyuki
Secon Department Of Internal Medicine Memorial Heart Center
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Fujioka Tomoaki
Department Of Urology And Physiology Ii Iwate Medical University School Of Medicine
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Kato Karen
Department of Hygiene and Preventive Medicine, School of Medicine, Iwate Medical University.
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