Hyponatremia Upon Resumption of Paroxetine Therapy
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概要
- 論文の詳細を見る
We present a 79-year-old woman with severe hyponatremia secondary to resumption of treatment with paroxetine, a selective serotonin-reuptake inhibitor antidepressant. Confusion and fatigue followed re-initiation of paroxetine after a 3-month hiatus. Hyponatremia, serum hypoosmolality, and urine hyperosmolality strongly suggested the syndrome of inappropriate secretion of antidiuretic hormone. Hyponatremia was quickly resolved after discontinuation of paroxetine and initiation of intravenous normal saline infusion together with oral fluid restriction. This case underscores the importance of monitoring serum sodium in elderly patients taking paroxetine, whether this represents a new prescription or reintroduction of the drug.
- 社団法人 日本内科学会の論文
- 2005-03-01
著者
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Nakajima Takahiro
Division of Gastroenterological Surgery, Department of Clinical Molecular Medicine, Kobe University
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Osame Mitsuhiro
Department Of Internal Medicine Faculty Of Medicine Kagoshima University
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Hamada Rikuzo
Division Of Neurology National Hospital Organization Kyushu Cardiovascular Center
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Osame Mitsuhiro
Department Of Neurology And Geriatrics Graduate School Of Medicine And Dental Sciences Kagoshima Uni
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Wakita Masayuki
Division Of Neurology National Hospital Organization Kyushu Cardiovascular Center
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MATSUOKA Hideki
Division of Neurology, National Hospital Organization Kyushu Cardiovascular Center
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OKATSU Hideki
Division of Neurology, National Hospital Organization Kyushu Cardiovascular Center
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Matsuoka Hideki
Division Of Neurology National Hospital Organization Kyushu Cardiovascular Center
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Nakajima Takahiro
Division Of Neurology National Hospital Organization Kyushu Cardiovascular Center
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Okatsu Hideki
Division Of Neurology National Hospital Organization Kyushu Cardiovascular Center
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