Alpha-fetoprotein (AFP)- and Des-gamma-carboxy Prothrombin (DCP)-producing Adenocarcinoma of the Stomach with Liver Metastasis in a Patient with Chronic Hepatitis C

元データ 2005-04-01 社団法人 日本内科学会

概要

A 45-year-old man was admitted to our hospital because of chronic hepatitis C and a large liver tumor accompanied by increased serum levels of alpha-fetoprotein (AFP) and des-gamma-carboxy prothrombin (DCP), the tumor markers for hepatocellular carcinoma. Endoscopic examination revealed advanced gastric cancer. Biopsy specimens of the stomach and liver showed gastric adenocarcinoma and its metastasis to the liver. Immunohistochemical studies demonstrated that adenocarcinoma cells both of the stomach and liver, were positive for the antibodies against AFP as well as DCP. Expression of AFP mRNA was shown in the cancer cells of the stomach. Accordingly, we diagnosed this patient with AFP- and DCP-producing adenocarcinoma of the stomach together with liver metastasis.

著者

Sakisaka Shotaro Department Of Gastroenterology And Medicine Faculty Of Medicine Fukuoka University
Sakisaka Shotaro Third Department Of Medicine Fukuoka University School Of Medicine
Inomata Shinjiro Department of Gastroenterology and Medicine, Faculty of Medicine, Fukuoka University
Sohda Tetsuro Department of Gastroenterology and Medicine, Faculty of Medicine, Fukuoka University
SOHDA Tetsuro Third Department of Medicine, Fukuoka University School of Medicine
WATANABE Hiroshi Third Department of Medicine, Fukuoka University School of Medicine
Sohda Tetsuro Department Of Gastroenterology And Medicine Faculty Of Medicine Fukuoka University
Inomata Shinjiro Department Of Gastroenterology And Medicine Faculty Of Medicine Fukuoka University
TOMIOKA Yoshitaka Third Department of Medicine, Fukuoka University, School of Medicine
INOMATA Shinjiro Third Department of Medicine, Fukuoka University, School of Medicine
MORITA Isamu Third Department of Medicine, Fukuoka University, School of Medicine
EGUCHI Koichi Third Department of Medicine, Fukuoka University, School of Medicine
AOYAGI Kunihiko Third Department of Medicine, Fukuoka University, School of Medicine
NAKAMURA Shotaro Nakamura Gastrointestinal Clinic
Morita Isamu Third Department Of Medicine Fukuoka University School Of Medicine
Sakisaka Shotaro Department Of Gastroenterology And Medicine Fukuoka University Faculty Of Medicine
Eguchi Koichi Department Of Gastroenterology And Medicine Faculty Of Medicine Fukuoka University
Sakisaka Shotaro Third Department Of Internal Medicine Fukuoka University
Aoyagi Kunihiko Department Of Gastroenterology And Medicine Faculty Of Medicine Fukuoka University
Aoyagi Kunihiko Third Department Of Medicine Fukuoka University School Of Medicine
Tomioka Yoshitaka Department Of Gastroenterology And Medicine Faculty Of Medicine Fukuoka University
Aoyagi Kunihiko Third Department Of Internal Medicine Fukuoka University School Of Medicine
Watanabe Hiroshi Department Of Hepatology Japanese Red Cross Fukuoka Hospital
Morita Isamu Department Of Gastroenterology Faculty Of Medicine Fukuoka University

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