De Novo Bone Formation Using Bovine Collagen and Platelet-rich Plasma in Animals
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概要
- 論文の詳細を見る
Recently, pepsin-digested collagen (so-called atelocollagen) has been used for tissue engineering as one of the most useful scaffolds for bone formation. Its excellent biocompatibility, due to its biological characteristics such, as absorbable properties and low antigenicity, has elevated collagen to become a primary resource in medical applications. Platelet-rich plasma (PRP) is an autologous vehicle that delivers a highly concentrated dose of platelets containing osteopromotive factors, such as platelet-derived growth factor (PDGF), and transforming growth factor beta-1 and beta-2 (TGF-P1 and TGF-P2). These growth factors are thought to help to induce local mesenchymal and epithelial cells to migrate, divide, and increase collagen synthesis. In this paper, the characteristics of bovine collagen, PRP and animal studies using them for bone formation are reviewed.
- 硬組織再生生物学会の論文
著者
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MURATA Masaru
Second Department of Oral Surgery, School of Dentistry, Health Sciences University of Hokkaido
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ARISUE Makoto
Second Department of Oral Surgery, School of Dentistry, Health Sciences University of Hokkaido
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Murata Masaru
Second Department Of Oral And Maxillofacial Surgery School Of Dentistry Health Sciences University O
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Arisue Makoto
Second Department Of Oral And Maxillofacial Surgery School Of Dentistry Health Sciences University O
関連論文
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- Induction of bone and cartilage by functionally graded-HAp/BMP-2 on rat skull periosteum(15thAnnual Meeting of the Society for Hard Tissue Regenerative Biology,Session 2)
- 17. Periosteum and bone augmentation by rhBMP-2/a telocollagen on adult rat skull.(8th Annual Meeting of the Society of Hard Tissue Biology July 24, 1999 in Asahikawa)
- Bone Healing in Large Mandibular Defects Without Periosteum in Adult Rabbits : A New Application of Collagenous Sponge for Bone Regeneration
- Calcifying odontogenic cyst in a 12-year-old girl
- De Novo Bone Formation Using Bovine Collagen and Platelet-rich Plasma in Animals