POEMS Syndrome Demonstrating VEGF Decrease by Ticlopidine
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概要
- 論文の詳細を見る
POEMS syndrome is a syndrome that presents with polyneuropathy, organomegaly, endocrinopathy, M-proteins and skin changes. Elevated vascular endothelial growth factor (VEGF) has recently been reported in POEMS syndrome. We report a case of POEMS syndrome with high VEGF titers. Steroid, plasmapheresis and intravenous gamma-globulin had little effect. Various immunosuppressive agents were discontinued due to side effects. Although administration of aspirin did not decrease VEGF, ticlopidine decreased VEGF significantly. This case suggests that ticlopidine is a candidate for supportive therapy in POEMS syndrome and we should measure VEGF before and after the administration of ticlopidine in other cases.
- 社団法人 日本内科学会の論文
- 2004-11-01
著者
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Oda Masaya
Department Of Neurology Sumitomo Hospital
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Oda Masaya
Department Of Gastrointestinal Medicine School Of Medicine Keio University
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KAMEYAMA Masakuni
Department of Medicine, Sumitomo Hospital
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Nishinaka Kazuto
Department Of Neurology Sumitomo Hospital
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Matsui Hideaki
Department Of Neurology Sumitomo Hospital
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Udaka Fukashi
Department Of Neurology Sumitomo Hospital
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KUBORI Tamotsu
Department of Neurology, Sumitomo Hospital
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Kubori Tamotsu
Department Of Neurology Sumitomo Hospital
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Kameyama Masakuni
Department Of Neurology Sumitomo Hospital
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Kameyama Masakuni
Department Of Medicine Sumitomo Hospital
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Kameyama Masakuni
Department of Gerontology, Faculty of Medicine, Kyoto University
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