オンライン呼吸気分析用質量分析計の^<13>C標識尿素を用いたヘリコバクター・ピロリ菌感染検査への応用

概要

論文の詳細を見る
In recent studies, it has been revealed that Helicobacter pylori (HP) causes stomach cancer, stomach ulcers, duodenal ulcers and chronic gastritis. The 13C-urea breath test (UBT) is one of the diagnostic methods for HP infection. A new UBT method with the respiratory mass spectrometer developed by authors continuously measures with on-line the amount of decomposed 13C-urea in the stomach after the administration of 13C-urea. Trial examinations by the new method were carried out with two subjects; one was diagnosed positive of HP infection and the other was negative by clinical examinations. Significant difference was found in the amount of decomposed 13C-urea between both subjects. The results presented in this paper demonstrate that the new UBT method is applicable to the clinical use in the diagnosis of HP infection.
日本質量分析学会の論文
1999-12-01