PCR-Based Genotyping of the Rat Atrn^<mv> Mutation
スポンサーリンク
概要
- 論文の詳細を見る
Rat myelin vacuolation mutation at the Attractin locus (Atrnmv) is a genomic deletion including the whole exon 1 of the Atrn gene. The precise size and location of the deleted region has not yet been identified because of poor information on genomic organization of the rat Atrn gene. Here, we identified the breakpoints of the Atrnmv mutation, using a draft sequence of the rat genome. In the Atrnmv/mv rat, a 6,914-bp genomic region was deleted. Primers flanked 5- and 3- breakpoints amplified the Atrnmv allele but not the wild-type allele. This primer set enables us to distinguish Atrnmv/+ heterozygous rats from Atrn+/+ rats, and will contribute to the efficient production of Atrnmv/mv rats.
- 社団法人 日本実験動物学会の論文
- 2004-01-01
著者
-
SERIKAWA Tadao
Institute of Laboratory Animals, Graduate School of Medicine, Kyoto University
-
KURAMOTO Takashi
Institute of Laboratory Animals, Faculty of Medicine, Kyoto University
-
Tokuda Satoko
Institute Of Laboratory Animals Graduate School Of Medicine Kyoto University
-
Serikawa Tadao
Institute For Laboratory Animals Faculty Of Medicine Kyoto University
-
庫本 高志
京都大学大学院医学研究科附属動物実験施設
-
Kuramoto Takashi
Carcinogenesis Division National Cancer Center Research Institute
-
Kuramoto Takashi
Institute Of Laboratory Animals Faculty Of Medicine Kyoto University
-
庫本 高志
京都大学 大学院医学研究科 附属動物実験施設
-
Kuramoto Takashi
Inst. Of Lab. Animals Graduate School Of Medicine Kyoto Univ.
関連論文
- ファンシーラットに由来する突然変異の遺伝解析
- プロトカドヘリン15遺伝子にナンセンス変異を持つ Kyoto circling ラット
- Serotonergic Modulation of Absence-Like Seizures in Groggy Rats: a Novel Rat Model of Absence Epilepsy
- A New Beige Mutant Rat ACI/N-Lyst^bg-Kyo
- Cloning of the 5' Upstream Region of the Rat p16 Gene and Its Role in Silencing
- A-25 Aspa/Atrn ダブルミュータントマウス作製による新規てんかんモデル動物の開発
- Antiepileptic Effects of Single and Repeated Oral Administrations of S-312-d, a Novel Calcium Channel Antagonist, on Tonic Convulsions in Spontaneously Epileptic Rats
- Involvement of Ca^ Channels in Abnormal Excitability of Hippocampal CA3 Pyramidal Cells in Noda Epileptic Rats
- IV F4 Inhibitory effects of levetiracetam on abnormal neurotransmission in hippocampal CA3 neurons of spontaneously epileptic rats(SER)
- Linkage Mapping of the Bra, Brb and Brg Genes for Rat Protein Phosphatase 2A 55 kDa B-Regulatory Subunit Isotypes
- An Allele-Specific Genotyping Method for Rat Lyst (Lysosomal Trafficking Regulator) Gene
- S-II-4b 染色体地図作製への応用 : ラット遺伝子地図の構築 : マイクロサテライトを用いた連鎖解析と蛍光 in situ hybridization
- Mapping of Four Simple Sequence Repeat(SSR) Markers on Rat Chromosome 4
- Kyoto Rhino Rats Derived by ENU Mutagenesis Undergo Congenital Hair Loss and Exhibit Focal Glomerulosclerosis
- Characterization of the Kyoto Circling (KCI) Rat Carrying a Spontaneous Nonsense Mutation in the Protocadherin 15 (Pcdh15) Gene
- Yoso-Tama-No-Kakehashi; The First Japanese Guidebook on Raising Rats
- 遺伝子改変ラットの作製システム
- Linkage Mapping of the Rat Msh2 DNA Mismatch Repair Gene on Chromosome 6
- MER Rat Strain: A New Type of Genetic Model in Epilepsy Research
- Involvement of Ca^ Channels in Abnormal Excitability of Hippocampal CA3 Pyramidal Cells in Noda Epileptic Rats
- ナショナルバイオリソースプロジェクト「ラット」
- NBRP-Rat の概要とラット胚・精子の保存状況
- Rat Mutations cvd and hob with Cerebellar Malformations Map to Chromosome 2
- 実験用ラットの有用性--ナショナルバイオリソースプロジェクト「ラット」
- Long-lasting Antiepileptic Effects of Levetiracetam against Epileptic Seizures in the Spontaneously Epileptic Rat (SER) : Differentiation of Levetiracetam from Conventional Antiepileptic Drugs
- Separation of Antiepileptogenic and Antiseizure Effects of Levetiracetam in the Spontaneously Epileptic Rat (SER)
- Activation by N-Acetyl-L-Aspartate of Acutely Dissociated Hippocampal Neurons in Rats via Metabotropic Glutamate Receptors
- IV F12 The hippocampal kindling in Noda epileptic rat(NER)
- IV F2 Is levetiracetam distinct from conventional antiepileptic drugs by antiepileptogenic properties in spontaneous epileptic rats?
- Enhanced Calcium Influx in Hippocampal CA3 Neurons of Spontaneously Epileptic Rats
- Inhibition by γ-Aminobutyric Acid System Activation of Epileptic Seizures in Spontaneously Epileptic Rats
- Antiepileptic Effects of 20-Hydroxyecdysone on Convulsive Seizures in Spontaneously Epileptic Rats
- Analysis and Comparison of New Candidate Loci for Hypertension between Genteic Hypertensive Rat Strains
- Genotyping Using Amp-FTA Method With Buccal Swab sample
- TM Rats: A Model for Platelet Storage Pool Deficiency
- A Novel Mutation vf Causing Abnormal Vacuoles in the Central Nervous System Maps on Rat Chromosome 8
- Chromosomal Mapping of Genes for Epilepsy in NER : A Rat Strain with Tonid-Clonic Seizures
- An Intergrated Rat Genome Map Based on Genetic and Cytogenetic Data
- Linkage Mapping of the Rat Interleukin 1 Receptor Antagonist Gene on Chromosome 3
- Junction Protein Locus on Chromosome 18 Cosegregates with Body Weight in the Spontaneously Hypertensive Rat
- A Comparative Genetic Map of Rat, Mouse and Human Genomes
- SII-1 自然発症てんかんラット(SER)発作原因遺伝子の検索
- Long-Term Antiepileptic Effects of Chronic Intake of CNK-602A, a Thyrotropin-Releasing Hormone Analogue, on Spontaneously Epileptic Rats
- Enhanced colitis-associated colon carcinogenesis in a novel Apc mutant rat
- PCR-Based Genotyping of the Rat Atrn^ Mutation
- Sex differences in the chemical induction of micronuclei in the rat
- Extension of Conserved Regions in the Rat and Mouse Genomes by Chromosomal Assignments of 29 Rat Genes
- Fourteen Anonymous DNA Markers of Laboratory Rats Identified with Arbitrarily Primed Polymerase Chain Reaction (AP-PCR)
- Production of WTC.ZI-zi Rat Congenic Strain and Its Pathological and Genetic Analyses
- Regional excitatory and inhibitory amino acid concentrations in Noda epileptic rat (NER) brain
- Pdx1, a Homeodomain Transcription Factor Required for Pancrease Development, Maps to Rat Chromosome 12
- Absence-Like and Tonic Seizures in Aspartoacylase/Attractin Double-Mutant Mice
- テクノ・トレンド 遺伝子改変マウスの「迅速・簡便・安全」なジェノタイピング法
- Identification of the Rat Rex Mutation as a 7-Bp Deletion at Splicing Acceptor Site of the Krt71 Gene
- Genetic Profiles of Three Inbred Strains Derived from Wild Rats (Rattus norvegicus) Trapped in Japan
- NBRP-Rat : New Integrated Research Platform
- ENUミュータジェネシス由来のKyoto rhinoラットは先天性脱毛と巣状糸球体硬化症を示す
- 養鼠玉のかけはし--日本における最初のラット飼育ガイドブック
- Serotonergic Modulation of Absence-Like Seizures in Groggy Rats : a Novel Rat Model of Absence Epilepsy
- 遺伝子ノックアウトマウスの作製法(F.解析する!-データを評価するための技術-,組織細胞化学の挑戦-臨床応用研究への飛躍)
- Identification of QTLs Involved in the Development of Amygdala Kindling in the Rat
- Infertility Associated with Meiotic Failure in the tremor Rat (tm/tm) is Caused by the Deletion of Spermatogenesis Associated 22
- Antiepileptic Effects of Single and Repeated Oral Administrations of S-312-d, a Novel Calcium Channel Antagonist, on Tonic Convulsions in Spontaneously Epileptic Rats
- Morphological Features of Adult Rats of IS/Kyoand IS-Tlk/Kyo Strains with Lumbar and Caudal Vertebral Anomalies