Alpha1-Antichymotrypsin Level in Cerebrospinal Fluid Is Closely Associated with Late Onset Alzheimer's Disease
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概要
- 論文の詳細を見る
The levels of α1-antichymotrypsin (ACT) in cerebrospinal fluid (CSF) from 66 sporadic Alzheimers disease (AD) patients and 54 normal controls were measured by enzyme immunoassay and compared. There was no correlation (r=0.259, n=54) between the ACT level and normal aging. The levels of ACT were significantly higher in the total AD group (p<0.01) than in the normal control group. Dividing AD patients into early onset AD (n=27) and late onset AD groups (n=39), the mean level of CSF ACT in the late onset AD group was significantly higher than that in the normal control group (p<0.001) and that in the early onset AD group (p<0.01). Thus, the level of ACT in CSF is closely associated with late onset AD.(Internal Medicine 34: 481-484, 1995)
- 社団法人 日本内科学会の論文
著者
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Shoji Mikio
Department Of Neurology Graduate School Of Medicine And Dentistry Okayama Univeristy
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Shoji Mikio
The Department Of Neurology Gunma University School Of Medicine
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Hirai Shunsaku
The Department Of Neurology
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Hirai Shunsaku
The Department Of Neurology Gunma University School Of Medicine
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MATSUBARA ETSURO
Department of Neurology, Graduate School of Medicine and Dentistry, Okayama University
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Hosoda Kenji
Diagnostics And Medicals Department Teijin Institute For Biomedical Research
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MATSUBARA Etsuro
The Department of Neurology, Okayama University Graduate Achool of Medicine and Dentistry.
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HARIGAYA Yasuo
Department of Neurology, Gunma University School of Medicine
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HARIGAYA Yasuo
the Department of Neurology, Gunma University School of Medicine
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NAKAMURA Tamiko
the Department of Neurology, Gunma University School of Medicine
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Harigaya Yasuo
Department Of Neurology Gunma University School Of Medicine
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Matsubara Etsuro
Department Of Neurology Division Of Neuroscience Biophysical Science Okayama University Graduate Sch
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Nakamura Tamiko
The Department Of Neurology Gunma University School Of Medicine
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Matsubara Etsuro
The Department Of Neurology Okayama University Graduate Achool Of Medicine And Dentistry.
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