Acute Myelogenous Leukemia with a t(2 ; 17 ; 4)(p13 ; q21 ; p16)Aberration : Effective Treatment with All-Trans Retinoic Acid and Granulocyte Colony-Stimulating Factor
スポンサーリンク
概要
- 論文の詳細を見る
The efficacy of all-trans retinoic acid (ATRA) in patients with acute promyeiocytic leukemia (APL) has been well documented. However, ATRA is not as effective against other types of acute myelogenous leukemia (AML) or myelodysplastic syndromes. We present a patient with AML (FAB: M2) associated with a t(2;17;4)(p13;q21;p16) chromosomal defect in which the 17q21 breakpoint was not within the retinoic acid receptor α locus which is typically rearranged in APL. This patient was successfully treated with ATRA and granulocyte colony-stimulating factor and improvement of hematological parameters lasted for 19 months without the use of cytotoxic agents.(Internal Medicine 38: 150-154, 1999)
- 社団法人 日本内科学会の論文
著者
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ISHIDA Fumihiro
Department of Internal Medicine, Shinshu University School of Medicine
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Kiyosawa Kendo
The Second Department Of Internal Medicine Shinshu University School Of Medicine
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Kitano K
The Second Department Of Internal Medicine Shinshu University School Of Medicine
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Ichikawa Naoaki
Department Of Hematology Nagano Red Cross Hospital
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SHIMODAIRA Shigetaka
The Department of Transfusion, Shinshu University Hospital
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ISHIDA Fumihiro
The Second Department of Internal Medicine, Shinshu University School of Medicine
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KITANO Kiyoshi
the Second Department of Internal Medicine, Shinshu University School of Medicine
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Ishida Fumihiro
Department Of Internal Medicine Shinshu University School Of Medicine
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Ishida Fumihiro
The Second Department Of Internal Medicine Shinshu University School Of Medicine
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Kitano Kiyoshi
The Second Department Of Internal Medicine Shinshu University School Of Medicine
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Kogure Katsuhiro
Division Of Genetic Therapeutics Center For Molecular Medicine Jichi Medical School Crest Japan Scie
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Matsui Hiroko
The Department Of Chromosome Analysis Second Section Srl Inc
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Shimodaira Shigetaka
The Department Of Transfusion Shinshu University Hospital
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Shimodaira Shigetaka
Second Department Of Internal Medicine Shinshu University School Of Medicine
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Ichikawa Naoaki
The Second Department Of Internal Medicine Shinshu University School Of Medicine
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SHIMODAIRA Shigetaka
The Second Department of Internal Medicine, Shinshu University School of Medicine
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NISHIZAWA Yoshio
The Second Department of Internal Medicine, Shinshu University School of Medicine
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KAMINO Ichiro
The Department of Chromosome Analysis, Second Section, SRL, Inc
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Kamino Ichiro
The Department Of Chromosome Analysis Second Section Srl Inc
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Nishizawa Yoshio
The Second Department Of Internal Medicine Shinshu University School Of Medicine
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Kiyosawa Kendo
The Second Department Of Internal Medicine Shinshu University School Medicine
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