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Institute For Drug Discovery Research Yamanouchi Pharmaceutical Co. | 論文
- 2-(3-Pyridyl)thiazolidine-4-carboxamide Derivatives. II. Structure-Activity Relationships and Active Configuration of 2-(3-Pyridyl)thiazolidine-4-carboxamides as Platelet-Activating Factor Receptor Antagonists
- 2-(3-Pyridyl)thiazolidine-4-carboxamides. 1. Novel Orally Active Antagonists of Platelet-Activating Factor (PAF)
- Long-term heart rate reduction by zatebradine, an If channel blocker attenuates ventricular remodeling and dysfunction after myocardial infarction in pigs
- Peptide Based Interleukin-1β Converting Enzyme (ICE) Inhibitors : Synthesis, Structure Activity Relationships and Crystallographic Study of the ICE-inhibitor Complex
- Synthesis and Structure-Activity Relationships in a Series of Ethenesulfonamide Derivatives, a Novel Class of Endothelin Receptor Antagonists
- Ethenesulfonamide Derivatives, a Novel Class of Orally Active Endothelin-A Receptor Antagonists
- Novel Potassium Channel Activators : Synthesis and Structure-Activity Relationship Studies of 3,4-Dihydro-2H-1,4-benzoxazine Derivatives
- Spiro-Substituted Piperidines as Neurokinin Receptor Antagonists. III. Synthesis of (±)-N-[2-(3,4-Dichlorophenyl)-4-(spiro-substituted piperidin-1'-yl)butyl]-N-methylbenzamides and Evaluation of NK_1-NK_2 Dual Antagonistic Activities
- Spiro-Substituted Piperidines as Neurokinin Receptor Antagonists. I. Design and Synthesis of (±)-N-[2-(3,4-Dichlorophenyl)-4-(spiro[isobenzofuran-1(3H), 4'-piperidin]-1'-yl)butyl]-N-methylbenzamide, YM-35375,as a New Lead Compound for Novel Neurokinin Rec
- An Easy Access to 7-Methyl-2-naphthalenecarbonitrile
- Biological Activity of Analogues of YM022. Novel (3-Amino Substituted Phenyl)urea Derivatives of 1,4-Benzodiazepin-2-one as Gastrin : Cholecystokinin-B Receptor Antagonists
- In Vivo Pharmacologic Profile of YM158, a New Dual Antagonist for Leukotriene D_4 and Thromboxane A_2 Receptors
- Effect of YM158, a Dual Lipid Mediator Antagonist, on Immediate and Late Asthmatic Responses, and on Airway Hyper-responsiveness in Guinea Pigs
- Studies on Nonpeptide Angiotensin II Receptor Antagonists. IV. Synthesis and Biological Evaluation of 4-Acrylamide-1H-imidazole Derivatives
- Studies on Nonpeptide Angiotensin II Receptor Antagonists. III. Synthesis and Biological Evaluation of 5-Alkylidene-3,5-dihydro-4H-imidazol-4-one-Derivatives
- Studies on Nonpeptide Angiotensin II Receptor Antagonists. II. Synthesis and Biological Evaluation of 5H-Pyrazolo[1,5-b][1,2,4]triazole Derivatives with a C-Linked Oxygen Functional Group at the 6-Position
- Studies no Nonpeptide Angiotensin II Receptor Antagonists. I. Synthesis and Biological Evaluation of Pyrazolo[1,5-b][1,2,4]triazole Derivatives with Alkyl Substituents
- Effect of Serotonin (5 - HT)_3 - Receptor Antagonists YM060, YM114 (KAE - 393), Ondasetron and Granisetron on 5 - HT_4 Receptors and Gastric Emptying in Rodents
- Protective Effect of a Pancreatic Elastase Inhibitor Against a Variety of Acute Pancreatitis in Rats
- Pancreatic Enzyme-Induced Pancreatitis and Systemic Complications in Rats
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