Kuzuya Nobuaki | 国立医薬食品衛生研究所薬物応答予測プロジェクト

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著作論文

Genetic Variations and Haplotypes of ABCC2 Encoding MRP2 in a Japanese Population
Genetic variations and haplotype structures of the DPYD gene encoding dihydropyrimidine dehydrogenase in Japanese and their ethnic differences
Genetic Variations of the ABC Transporter Gene ABCB11 Encoding the Human Bile Salt Export Pump (BSEP) in a Japanese Population
日本人におけるGSTT1及びGSTM1の遺伝子多型の同定及びハプロタイプ構造の解析
Twenty Novel Genetic Variations and Haplotype Structures of the DCK Gene Encoding Human Deoxycytidine Kinase (dCK)
Genetic Variations of VDR/NR1I1 Encoding Vitamin D Receptor in a Japanese Population
Genetic Variations and Frequencies of Major Haplotypes in SLCO1B1 Encoding the Transporter OATP1B1 in Japanese Subjects : SLCO1B1^*17 is More Prevalent Than ^*15
Genetic Variations and Haplotype Structures of the ABC Transporter Gene ABCC1 in a Japanese Population
Fourteen Novel Genetic Variations and Haplotype Structures of the TYMS Gene Encoding Human Thymidylate Synthase (TS)
日本人における Denaturing HPLC を用いた Thiopurine S-Methyltransferase 遺伝子の新規SNPスクリーニング
日本人におけるヒトSLC29A1の新規遺伝子多型の同定
Genetic Variation and Haplotype Structure of the ABC Transporter Gene ABCG2 in a Japanese Population
Genetic Variations and Haplotypes of UGT1A4 in a Japanese Population
Genetic Polymorphisms of UGT1A6 in a Japanese Population
Non-synonymous Single Nucleotide Alterations Found in the CYP2C8 Gene Result in Reduced in Vitro Paclitaxel Metabolism
Identification of prognostic biomarkers in gastric cancer using endoscopic biopsy samples
Antibody-dependent cellular cytotoxicity of cetuximab against tumor cells with wild-type or mutant epidermal growth factor receptor
Synergistic interactions between the synthetic retinoid tamibarotene and glucocorticoids in human myeloma cells
A literature review of molecular markers predictive of clinical response to cytotoxic chemotherapy in patients with breast cancer
Pertuzumab, a novel HER dimerization inhibitor, inhibits the growth of human lung cancer cells mediated by the HER3 signaling pathway
Anticancer effects of ZD6474, a VEGF receptor tyrosine kinase inhibitor, in gefitinib ("Iressa")-sensitive and resistant xenograft models
Antitumor activity of TZT-1027 (Soblidotin) against vascular endothelial growth factor-secreting human lung cancer in vivo
Reversal of Cisplatin Resistance by the 1,4-Benzothiazepine Derivative, JTV-519
CPT-11 Alters the Circadian Rhythm of Dihydropyrimidine Dehydrogenase mRNA in Mouse Liver
Enhancement of Cisplatin Sensitivity in High Mobility Group 2 cDNA-transfected Human Lung Cancer Cells
Characterization of a Human Small-cell Lung Cancer Cell Line Resistant to a New Water-soluble Camptothecin Derivative, DX-8951f
Preferential Binding of E7010 to Murine β3-Tubulin and Decreased β3-Tubulin in E7010-resistant Cell Lines
In vitro Enhancement of Antitumor Activity of a Water-soluble Duocarmycin Derivative, KW-2189, by Caffeine-mediated DNA-repair Inhibition in Human Lung Cancer Cells
p16^ Expression Is Associated with the Increased Sensitivity of Human Non-small Cell Lung Cancer Cells to DNA Topoisomerase I Inhibitors
Interferon-γ-inducing Factor Gene Transfection into Lewis Lung Carcinoma Cells Reduces Tumorigenicity in vivo
Effect of Glutathione Depletion on Cisplatin Resistance in Cancer Cells Transfected with the γ-Glutamylcysteine Synthetase Gene
A Topoisomerase II Inhibitor, NK109, Induces DNA Single- and Double-strand Breaks and Apoptosis
Effect of suramin on cdc2 kinase activity of the purified enzyme and from the crude extracts from lung cancer cells
日本人におけるABCC3遺伝子の多型解析
Enhancement of in vivo Antitumor Activity of a Novel Antimitotic 1-Phenylpropenone Derivative, AM-132, by Tumor Necrosis Factor-α or Interleukin-6
Intracellular Carboxyl Esterase Activity Is a Determinant of Cellular Sensitivity to the Antineoplastic Agent KW-2189 in Cell Lines Resistant to Cisplatin and CPT-11
Association of epidermal growth factor receptor (EGFR) gene mutations with EGFR amplification in advanced non-small cell lung cancer
N-Glycan fucosylation of epidermal growth factor receptor modulates receptor activity and sensitivity to epidermal growth factor receptor tyrosine kinase inhibitor
Epidermal growth factor receptor lacking C-terminal autophosphorylation sites retains signal transduction and high sensitivity to epidermal growth factor receptor tyrosine kinase inhibitor
Effects of Src inhibitors on cell growth and epidermal growth factor receptor and MET signaling in gefitinib-resistant non-small cell lung cancer cells with acquired MET amplification
Genetic Polymorphisms of Copper- and Platinum Drug-efflux Transporters ATP7A and ATP7B in Japanese Cancer Patients
Ethnic Differences of two Non-synonymous Single Nucleotide Polymorphisms in CDA Gene
Translational and clinical studies of target-based cancer therapy
Bortezomib potentially inhibits cellular growth of vascular endothelial cells through suppression of G2/M transition
Prediction of Severe Adverse Drug Reactions Using Pharmacogenetic Biomarkers
Genetic Polymorphisms of FCGRT Encoding FcRn in a Japanese Population and Their Functional Analysis
Plasma concentrations of VCAM-1 and PAI-1 : A predictive biomarker for post-operative recurrence in colorectal cancer

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