In vivo Ultrahigh-Resolution Ophthalmic Optical Coherence Tomography Using Gaussian-Shaped Supercontinuum

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概要

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• We have demonstrated the in vivo ultrahigh-resolution optical coherence tomography (OCT) imaging of the human eye using a Gaussian-shaped supercontinuum source. Using an ultrashort-pulse Ti:sapphire laser and a polarization-maintaining single-mode fiber, a linearly polarized, high-power, low-noise, Gaussian-shaped supercontinuum is generated in the wavelength region from 700 to 950 nm. For ophthalmic imaging, a wideband Gaussian-shaped supercontinuum with a bandwidth of 140 nm is generated at a center wavelength of 830 nm. The observed axial resolutions are 2.9 μm in air and 2.1 μm in tissue. The generated supercontinuum is combined with a modified ophthalmic OCT system, and sidelobe-free ultrahigh-resolution OCT images of the human retina and cornea are obtained.

• 2010-01-25

著者

• Nishizawa Norihiko

  Division Of Advanced Science And Biotechnology Graduate School Of Engineering Osaka University

• Ito Yasuki

  Department Of Ophthalmology Nagoya University Graduate School Of Medicine

• Nishiura Masahiro

  Department of Quantum Engineering, Nagoya University, Nagoya 464-8603, Japan

• Kobayashi Toshihiro

  Engineering Development Department, NIDEK Co., Ltd., Gamagori, Aichi 443-0038, Japan

• Adachi Muneyuki

  Engineering Development Department, NIDEK Co., Ltd., Gamagori, Aichi 443-0038, Japan

• Nakanishi Jun

  Engineering Development Department, NIDEK Co., Ltd., Gamagori, Aichi 443-0038, Japan

• Ueno Tokio

  Engineering Development Department, NIDEK Co., Ltd., Gamagori, Aichi 443-0038, Japan

• Ito Yasuki

  Department of Ophthalmology, School of Medicine, Nagoya University, Nagoya 466-8550, Japan

• Nishizawa Norihiko

  Division of Advanced Science and Biotechnology, Osaka University, Suita, Osaka 565-0871, Japan

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