Measurement of Optical Coefficients of Tissue-like Solutions using a Combination Method of Infinite and Semi-infinite Geometries with Continuous Near Infrared Light

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This paper proposes a new continuous wave (CW) method to measure the optical coefficients of a tissue-like solution by using a combination of infinite and semi-infinite geometries. Previous CW methods have required a long source–detector separation distance to distinguish the effects of absorption from scattering. This long separation distance results in inaccurate optical coefficients due to a low signal-to-noise ratio (SNR). A combination method is suitable for measuring optical coefficients of tissue-like solutions while using a short source–detector distance to increase the accuracy of the CW method. The measurement geometries are switched by an optical system, and light is detected at an avalanche photo-detector (APD). The absorption and reduced scattering coefficients are calculated from the slope and intercept values of a straight line derived from the fluence rate at several source–detector distances. The combination method provides an excellent separation performance between scattering and absorption with continuous near infrared (NIR) light.
Published by the Japan Society of Applied Physics through the Institute of Pure and Applied Physicsの論文
2006-09-15