Pressure Gradient Estimation Based on Ultrasonic Blood Flow Measurement
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概要
- 論文の詳細を見る
Mechanical load to the blood vessel wall, such as shear stress and pressure, which occurs in blood flow dynamics, contribute greatly to plaque rupture in arteriosclerosis and to biochemical activation of endothelial cells. Therefore, noninvasive estimations of these mechanical loads are able to provide useful information for the prevention of vascular diseases. Although the pressure is the dominant component of mechanical load, for practical purposes, the pressure gradient is also often important. So far, we have investigated the estimation of the kinematic viscosity coefficient using a combination of the Navier-Stokes equations and ultrasonic velocity measurement. In this paper, a method for pressure gradient estimation using the estimated kinematic viscosity coefficient is proposed. The validity of the proposed method was investigated on the basis of the analysis with the data obtained by computer simulation and a flow phantom experiment. These results revealed that the proposed method can provide a valid estimation of the pressure gradient.
- Published by the Japan Society of Applied Physics through the Institute of Pure and Applied Physicsの論文
- 2006-05-30
著者
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Nitta Naotaka
Institute For Human Science And Biomedical Engineering National Institute Of Advanced Industrial Sci
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Homma Kazuhiro
Institute For Human Science And Biomedical Engineering National Institute Of Advanced Industrial Sci
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Shiina Tsuyoshi
Graduate School Of Medicine Kyoto University
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Homma Kazuhiro
Institute for Human Science and Biomedical Engineering, National Institute of Advanced Industrial Science and Technology (AIST), 1-2-1 Namiki, Tsukuba, Ibaraki 305-8564, Japan
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Shiina Tsuyoshi
Graduate School of Systems and Information Engineering, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki 305-8573, Japan
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