Noninvasive Temperature Estimation in Oncology Hyperthermia Using Phase Changes in Pulse–Echo Ultrasonic Signals

概要

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An accurate and noninvasive temperature measurement inside phantoms and tissues is important to improve hyperthermia treatment. The use of ultrasonic echo-pulses for this purpose is a promising line of research. In this paper, we propose an alternative method for processing echo-signals received from inner regions in phantoms. Ultrasonic estimation of temperature is carried out using a phase demodulation technique, which gauges the indirect effects in the phase domain of the previously reported time-shifts in the echo position. The potential performance and high sensitivity of this procedure is explained and verified with several simulated examples. Finally, the proposed procedure is applied to the experimental assessment of phase changes with temperature in ultrasonic echoes successively acquired from different milieus. In all cases, the results show good performance and high sensitivity. This is an interesting alternative to measurements in waveforms of the very small delays (nanoseconds) associated with this ultrasonic temperature estimation.
Published by the Japan Society of Applied Physics through the Institute of Pure and Applied Physicsの論文
2006-10-15