Guiding Molecular Motors with Nano-Imprinted Structures
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概要
- 論文の詳細を見る
This work, for the first time, demonstrates that nano-imprinted samples, with 100 nm wide polymer lines, can act as guides for molecular motors consisting of motor proteins actin and myosin. The motor protein function was characterized using fluorescence microscopy and compared to actomyosin motility on non-structured nitrocellulose surfaces. Our results open for further use of the nano-imprint technique in the production of disposable chips for bio-nanotechnological applications and miniaturized biological test systems. We discuss how the nano-imprinted motor protein assay system may be optimized and also how it compares to previously tested assay systems involving low-resolution UV-lithography and low throughput but high-resolution electron beam lithography.
- Published by the Japan Society of Applied Physics through the Institute of Pure and Applied Physicsの論文
- 2005-05-15
著者
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Mansson Alf
Department Of Chemistry And Biomedical Sciences University Of Kalmar
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CARLBERG Patrick
Division of Solid State Physics and The Nanometer Consortium, Lund University
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Bunk Richard
Division Of Solid State Physics And The Nanometer Consortium Lund University
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Omling Par
Division Of Solid State Physics And The Nanometer Consortium Lund University
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Nicholls Ian
Department Of Chemistry & Biomedical Sciences University Of Kalmar
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Tagerud Sven
Department Of Chemistry And Biomedical Sciences University Of Kalmar
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Sundberg Mark
Department Of Chemistry And Biomedical Sciences University Of Kalmar
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Montelius Lars
Division Of Solid State Physics And The Nanometer Consortium Lund University
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Nicholls Ian
Department of Chemistry and Biomedical Sciences, University of Kalmar, Kalmar S-391 82, Sweden
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Montelius Lars
Division of Solid State Physics and The Nanometer Consortium, Lund University, Box 118, Lund S-221 00, Sweden
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Sundberg Mark
Department of Chemistry and Biomedical Sciences, University of Kalmar, Kalmar S-391 82, Sweden
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Omling Pär
Division of Solid State Physics and The Nanometer Consortium, Lund University, Box 118, Lund S-221 00, Sweden
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Carlberg Patrick
Division of Solid State Physics and The Nanometer Consortium, Lund University, Box 118, Lund S-221 00, Sweden
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Bunk Richard
Division of Solid State Physics and The Nanometer Consortium, Lund University, Box 118, Lund S-221 00, Sweden
関連論文
- Guiding Molecular Motors with Nano-Imprinted Structures
- Molecularly imprinted polymers in separation science
- Guiding Molecular Motors with Nano-Imprinted Structures