Erythrocyte Deformability and its Hemorheological Consideration

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概要

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• The suspension of hardened erythrocytes (red blood cells) differs from the suspension of normal erythrocytes with respect to their rheological behavior. The deformability of normal and hardened erythrocytes (obtained by heating blood at 49°C or by incubating erythrocytes in a solution of hydrogen peroxide) was measured with a slit diffractometer and erythrocyte suspension viscosity was measured with a rotational viscometer. We found that when erythrocytes were heated at 49°C, with much less deformability than normal erythrocytes, their suspension viscosity was almost the same as the normal blood viscosity at high shear rates, whereas when erythrocytes were incubated in a solution of hydrogen peroxide, with an intermediate decrease of deformability, their suspension viscosity was greatly increased. The present study concluded that not all rigid cells cause an increase in blood viscosity at high shear rates, and therefore that decreased cell deformability is not always a good indicator of high-shear blood viscosity.

• Published by the Japan Society of Applied Physics through the Institute of Pure and Applied Physicsの論文
• 2004-12-15

著者

• Park Myung-Su

  School of Mechanical Engineering, Kyungpook National University, Daegu 702-701, Korea

• Ku Yunhee

  School of Mechanical Engineering, Kyungpook National University, Daegu 702-701, Korea

• Suh Jang-Soo

  Department of Laboratory Medicine, School of Medicine, Kyungpook National University, Daegu 700-412, Korea

• Shin Sehyun

  School of Mechanical Engineering, Kyungpook National University, Daegu 702-701, Korea

• Shin Sehyun

  School of Mechanical Engineering, Kyungpook National University, 1370 Sankyuk-dong Buk-gu, Daegu 702-701, Korea

関連論文

• Erythrocyte Deformability and its Hemorheological Consideration
• Characteristics of Shear-Thinning Fluid Flow under Traversal Vibration

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