管腔外発育形態を示した胃Gastrointestinal Stromal Tumorの2例

概要

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Recently, a new concept of gastrointestinal stromal tumor (GIST) has been advocated to the tumor which is originated in the mesenchymal tissue. We report on two cases of gastric GIST with extraluminal growth. Case 1 : A 58-year-old male was pointed out a lesion in the upper corpus of the stomach by gastric mass survey in 1997. The lesion was formed with pressure from outside of the gastric wall. The endoscopic examination using an ultrasonic probe showed the hyperechoic mass, 5 cm in diameter, which had the continuity with the fourth layer of the gastric wall. Partial gastrectomy was performed because the malignancy could not be excluded. The lesion was composed of spindleshaped cells and diagnosed as GIST by immunohistochemical study. Case 2 : A 74-year-old female was pointed out a submucosal tumor, 1.2cm in size, in the upper corpus of the stomach by gastric mass survey in 1998. Endoscopic ultrasonography revealed the homogeneous hypoechoic mass, 5 cm in diameter, which developed to outside of the stomach and had the continuity with the fourth layer of the gastric wall. It was resected and diagnosed as GIST by immunohistochemical study. We are not aware of any reports of a case of GIST with the extraluminal growth, which was demonstrated by ultrasonic endoscopy.
Japan Gastroenterological Endoscopy Society Kanto Chapterの論文