喉頭上皮過形成症の臨床統計と治療

概要

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A total of 217 patients with epithelial hyperplasia of the larynx were treated between 1971 and 1990. The majority of the patients were male smokers. Most patients between 50 and 60 years old. Between 1981 and 1990, conservative treatment was given to 65 patients with non-massive lesions, and 60% showed improvement. Discontinuation of smoking during conservative treatment affected the incidence of improvement. Ninety one patients were treated with endolaryngeal microscopic CO2 laser surgery between 1978 and 1990. Fifteen patients developed recurrence. The recurrent lesion was benign epithelial hyperplasia in eight and invasive carcinoma in seven. Only male and preoperative smokers had recurrence. Discontinuation of smoking following laser surgery did not affect the incidence of recurrence. The incidence of recurrence and cancer development in severe dysplasia cases was lower than that among patients who were not treated by CO2 laser.
耳鼻咽喉科臨床学会の論文