PIV Analysis of Cartilage Regeneration Process from Bone Marrow Cells by Three Dimensional Culture using RWV Bioreactor

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概要

• 論文の詳細を見る

• Why do mesenchymal stem cells (MSCs) regenerate good cartilage tissue in vitro under condition of microgravity generated by a rotating vessel? To answer this question, we developed a PIV measuring apparatus equipped with a RWV (rotating wall vessel) bioreactor, which enabled visualization of the three dimensional medium flow applied to the aggregated cartilaginous cells. The spacial distribution of cartilage marker genes (sox-9, aggrecan, and collagen type II) was measured using a microdisection system and discussed in association with the PIV results.

• ナノ・バイオメディカル学会の論文

著者

• UEMURA Toshimasa

  Nanosystem Research Institute (NRI), National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Japan

• UEMURA Toshimasa

  Nanosystem Research Institute (NRI), National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Japan.

関連論文

• Construction of Three Dimensional Tissues of Osteosarcoma MG63 Cells Using a Rotating Wall Vessel Bioreactor and the Dose-Dependent Effect of Doxorubicin
• PIV Analysis of Cartilage Regeneration Process from Bone Marrow Cells by Three Dimensional Culture using RWV Bioreactor

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