Transformation from Multi to Single Lamellar Vesicle by Addition of a Cationic Lipid to DLPC Explored with SAXS and TEM
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概要
- 論文の詳細を見る
DLPC (1, 2-dilauroyl-sn-glycero-3-phosphocholine) is one of the major lipids constituting of cellular membranes. When DLPC itself is dispersed in aqueous solutions, multi-lamellar vesicles are formed although the cellular membranes are made of single bilayers. We found that the addition of a calix[4]arene derivative (CaL[4]C3) bearing four amine groups as headgroup to the DLPC multi-lamellar vesicle induced the structural transformation to a single-lamellar vesicle by use of small angle X-ray scattering and electron microscopy, indicating that the highly condensed ionic groups of CaL[4]C3 are useful to controls the membrane morphology.
- 公益社団法人 日本化学会の論文
著者
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SAKURAI Kazuo
Department of Chemical Process & Environments, Faculty of Environmental Engineering, The University
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Yasunaga Takuo
Depart. Biosci. Bioinfor. Comp. Sci. Sys. Eng. Kyushu Inst. Technol.
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Sanada Yusuke
Department Of Advanced Materials Science Graduate School Of Frontier Sciences University Of Tokyo Kashiwa
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Takahara Atsushi
Structural Materials Science Laboratory SPring-8 Center, RIKEN Harima Institute Research
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Kubo Genki
Department of Chemistry and Biochemistry, The University of Kitakyushu
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Sakamoto Shunsuke
Department of Chemistry and Biochemistry, The University of Kitakyushu
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Fujii Shota
Structural Materials Science Laboratory SPring-8 Center, RIKEN Harima Institute Research
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