Synthesis of a Natural Chromenoquinone via the Diels–Alder Reaction of Pyranobenzyne and Furan

スポンサーリンク

概要

• 論文の詳細を見る

• We describe the total synthesis of angular chromenoquinone 1 isolated from Conospermum plants. Iodophenol, a precursor of pyranobenzyne, was prepared by Claisen rearrangement of an iodoresorcinol derivative. Diels–Alder reaction of the pyranobenzyne and a substituted furan proceeded in low regioselectivity to afford desired 1 and its regioisomer.

• 公益社団法人 日本薬学会の論文

著者

• Kumamoto Takuya

  Department Of Medicinal Organic Chemistry Graduate School Of Pharmaceutical Sciences Chiba Universit

• Kumamoto Takuya

  Department of Synthetic Organic Chemistry, Research Institute of Pharmaceutical Sciences, Musashino University

• Katakawa Kazuaki

  Department of Synthetic Organic Chemistry, Research Institute of Pharmaceutical Sciences, Musashino University

• Sato Ayaka

  Department of Synthetic Organic Chemistry, Research Institute of Pharmaceutical Sciences, Musashino University

• Iwasaki Mari

  Department of Synthetic Organic Chemistry, Research Institute of Pharmaceutical Sciences, Musashino University

• Horikawa Tomofumi

  Department of Synthetic Organic Chemistry, Research Institute of Pharmaceutical Sciences, Musashino University

関連論文

• The structure-activity relationship between oxycoumarin derivatives showing inhibitory effects on iNOS in mouse macrophage RAW264.7 cells
• Isolation of Acridone Alkaloids and N-[(4-Monoterpenyloxy)phenylethyl]-Substituted Sulfur-Containing Propanamide Derivatives from Glycosmis parva and Their Anti-herpes Simplex Virus Activity
• Inhibitory effect of the extracts from Thai medicinal plants on iNOS expression in mouse macrophage RAW 264.7
• Inhibitory effect of oxycoumarins isolated from the Thai medicinal plant Clausena guillauminii on the inflammation mediators, iNOS, TNF-α, and COX-2 expression in mouse macrophage RAW 264.7
• Antiallergic Activity of Curcuma longa (II) : Features of inhibitory actions on histamine release from mast cells
• Antiallergic Activity of Curcuma longa (I) : Effectiveness of Extracts Containing Curcuminoids
• New 2-Aryl-1,4-naphthoquinone-1-oxime Methyl Ether Compound Induces Microtubule Depolymerization and Subsequent Apoptosis
• Synthesis of a Natural Chromenoquinone via the Diels–Alder Reaction of Pyranobenzyne and Furan

スポンサーリンク