A Case of Atopic Dermatitis Successfully Treated with Suplatast Tosilate

概要

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A 22-year-old man was referred to our clinic because of a severe skin eruption, which was diagnosed as atopic dermatitis in childhood and treated with various therapeutic modalities. On examination, he had a generalized eczematous eruption with an exudative change. His face was reddish, pigmented and exudative as well. The patient was treated with oral olopatadine and topical steroid. Although the exudative change was reduced by this therapy, his eruption still remained with newly developed erythematous lesions. Thus, we treated him additionally with oral suplatast tosilate, which remarkably improved the skin lesions. Along with reduction of the skin severity index, IgE was decreased from 8,000 to 3,673 units/ml, and the number of eosinophils from 10.7 to 5.6%. Our case demonstrated that suplatast tosilate exerts a therapeutic effectiveness for atopic dermatitis as IgE depressor more efficaciously in combination with another complementary drug.
日本皮膚科学会大阪地方会・日本皮膚科学会京滋地方会の論文