耳科用吸引管の考察と試作

概要

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Aspirin is injected to the guinea pigs to understand its effects on the cochlear nerve excitability. For this purpose, the compound AP's evoked by electrical stimulation to the cochlea, were recorded using micropipettes introduced in the cochlear nerve bundle. The latency of compound AP's was found to be increased. In one of our previous studies we observed that the cochlear nerve spontaneous discharge rate also increases following the injection of Aspirin. These two results indicate that Aspirin suppresses the cochlear nerve excitability and the decreased excitability contributes to the impairment of hearing function.
日本耳科学会の論文