Experimental Studies on Inner Ear Barotrauma -With Emphasis on EP-

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Sudden atmospheric pressure changes was given to many guinea pigs in a chamber. After pressure loading, we measured endochlear dc potential in guinea pigs without Preyer reflex, and we investigated whether negative EP after anoxia should appear or not.<BR>Endocochlear dc potential decreased immediately after barotrauma but it returned to normal values in two weeks.<BR>The anoxic EP in barotrauma animals less then 3 days after the pressure loading decreased to negative values, but the anoxic EP in barotrauma animals more than 7 days after the pressure loading never decreased to negative values. They remained in positive values. These findings suggest that inner ear mechanisms maintaining positive EP is damaged immediately after barotrauma and that its function is restored in 7-14 days.
日本耳科学会の論文