OXYGEN SUPPLY TO THE TYMPANIC PERILYMPH VIA ROUND WINDOW MEMBRANE
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概要
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Dynamic changes in the oxygen tension in scala tympani was measured through a small hole drilled in the bony wall of the basal turn cochlea using the poralographic technique. The oxygen consumption of the inner ear was calculated by the following equation. V (dC/dt) =q<SUB>1</SUB>+q<SUB>2</SUB>-q<SUB>3</SUB>, where V represents the volume of the tympanic perilymph, dC/dt the time differentiation of the oxygen tension, q<SUB>1</SUB> the oxygen supply through the round window membrane, q<SUB>2</SUB> the oxygen supply through theinner ear vessels, and q<SUB>3</SUB> the oxygen consumption of the inner ear tissue. The results to be drawn from the study are ; 1) The oxygen consumption rate is 1.73×10<SUB>-1</SUB>mL/100g/min. 2) Autoregulation of the inner ear vessels is present. 3) Oxygen supply to the tympanic perilymph through the round window membrane is approximately 14% in the room air and can be elevated as high as 79% in pure oxygen compared with that of the inner ear vessels.
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