Dynamics of Inner Ear Fluid Electrolytes after Peroral Administration of Glycerol
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概要
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Serum, CSF, scala tympani perilymph and scala vestibuli perilymph werecollected from normal guinea pigs both before and after peroral administration of 50% Glycerol (12ml/kg), and the sodium and potassium concentration were assessed using a microflamephotometer.<BR>Substantial increases in sodium concetration were found in scala tympani perilymph, scala vestibuli perilymph, and CSF, while no significant change was observed in serum.<BR>Increases in potassium concentration were found in the same fluids in which the sodium concentration increased.<BR>These results are considered to have been caused by dehydration induced by the osmotic agent, Glycerol.
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