The total lung function in bronchial asthma. 1. Variation of lung functon in the symptomatic and asymptomatic stage in the same cases.:1. VARIATION OF LUNG FUNCTON IN THE SYMPTOMATIC AND ASYMPTOMATIC STAGE IN THE SAME CASES
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Reversible bronchoconstriction is one of the fundamental characteristics of bronchial asthma.We studied 28 asthmatic patients by different lung function tests and compared the data of each individual during the attack from during without attack to clarify the site and the extent of bronchoconstriction.(1) The decrease of %VC and the increase of RV/TLC were found significantly in symptomatic stage. (p<0. 01) It was suggested that the overinflation of lung occurred by airway clousure.(2) Peak flow and Vmax measured by Flow volume curve decreased in all cases in symptomatic stage. Though these findings were shown in the aggravation of broncho-constriction, these were not necessary to indicate the site of bronchoconstriction.(3) CV/VC was not found to be significantly different between them, but the site of bronchoconstriction in symptomatic stage was found in two types, one indicated small airways constriction predominant type and another large airways constriction predominant type in view of the variation of CV/VC.(4) A tendency to increase in %DLco was found in symptomatic stage. Further stu-dies are needed to clarify this mechanism.
- 一般社団法人 国立医療学会の論文
一般社団法人 国立医療学会 | 論文
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