The total lung function in bronchial asthma. 2. The lung function in steroid dependent bronchial asthma.:2. THE LUNG FUNCTION IN STEROID DEPENDENT BRONCHIAL ASTHMA

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In order to evaluate the pulmonary functional characteristic of steroid dependent bron-chial asthma (DEP), we compared the lung functional parameters with steroid independent bronchial asthma (IND) and bronchial asthma with chronic pulmonary emphysema (BA+CPE) in separate age. Of the 103 cases with bronchial asthma, 24 cases (23.3%) of DEP were recognized, and 6 of them were associated with both aspirin-induced asthma and nasal polyp.The overinf lation of lung as shown in the significant high ratio of residual volume to total lung capacity and the nonuniform distribution of inspired gas as shown in the significant high value of ΔN2 were found in DEP of ages from 30 to 59 years. In addition to these findings the obstructive disturbance was highly significant in DEP.Though the lung functional disturbance of the same degree as IND was found in DEP of over 60 years, the value of ΔN2 was found to be significantly different between DEP and IND, and the nonuniform distribution of inspired gas was similarly suggested.It is suggested that the higher collapse of the small airway due to the destroyed parenchyma of lung and the lower volume of pulmonary diffusing capacity due to the destroyed alveoli were found in the pulmonary function of BA+CPE.
一般社団法人国立医療学会の論文