Regional cerebral blood flow using 133Xenon intra-venous technique. (1). Regional cerebral blood flow and the reactivity of blood vessels in normal control group.:(1) —REGIONAL CEREBRAL BLOOD FLOW AND THE REACTIVITY OF BLOOD VESSELS IN NORMAL CONTROL GROU

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We used the noninvasive 133Xenon venous technique to measure 3622 regional cerebral blood flows (rCBFs) in 1955 cases for last about six years. The majority of patients was fifty and sixty decades in age, and their diagnosis was ischemic cerebrovasculer disease. Sixty-four healty, non-hospitalized volunteers(10-76 years)were studied as control value. The age-related curve of rCBF showed a rapid decrease in young age groups and a gradual decrease in older age groups. The curve was well fitted to the hyperbola (X-13.0621) (Y-42.6038) =556.493. The correlation coefficient was 0.93. This finding showed that the declined rCBF related with age was attributed to more than two factors. When cerebro-vascular CO2 reactivity was tested in the healty control group, the rCBF on average increased to 90.5 ml/100g/min from 70.2ml/100g/min (28.9%) being accompanied with the elevation of PCO2 of 11.4mmHg in arterial blood gas on average. The CO2 reactivity index was 2.75±1.65 on average. On the other hand, following an intravenous injection of Diamox (1g) the rCBF increased to 80.0ml/100g/min from 59.6ml/100g/min (34.2%) on average in the control group.
一般社団法人国立医療学会の論文