Lecithin: Cholesterol acyltransferase, serum total cholesterol and HDL-cholesterol during pregnancy and postpartum.
スポンサーリンク
概要
- 論文の詳細を見る
The changes in lecithin: cholesterol acyltransferase (LCAT) activity during pregnancy and postpartum have been seldom reported. In this study LCAT activity in the second and third trimesters of pregnancy and postpartum was examined as well as serum total cholesterol (TC) and HDL-cholesterol (HDL-C). Twenty-six normal women (age range 20-33 years) were studied at the 15th week of pregnancy, in the third trimester (32nd, 34th, 36th and 38th week) and at 35.9±6.9 (SD) days (28-44 days) postpartum.LCAT activity increased from 78±15 nmol/ml/h at the 15th week to 91±17nmol/ml/h at the 32nd week (p<0.05), and remained at about this level until the 38th week. It decreased after delivery, and by 35.9±6.9 days had reached 64±15nmol/ml/h. This was still much lower than the mean at the 15th week of pregnancy (p<0.01). TC level rose from 184±25mg/dl at the 15th week to 244±51mg/dl at the 32nd week (p<0.01), and to 259±47mg/dl at the 38th week (p<0.001). No significant difference was found between TC at the 32nd week and 38th week of pregnancy. TC reached 228±45 mg/dl at 35.9±6.9 days postpartum. This was lower than the mean at the 36th or 38th week of pregnancy (p<0.05, respectively). There was no significant difference between TC at the 32nd or 34th week of pregnancy and postpartum. TC after delivery was much higher than the mean at the 15th week of pregnancy (p<0.001). HDL-C remained steady from the 15th to the 38th week at about the mean of 70mg/dl and fell to 66±20 mg/dl postpartum. No significant difference was found between HDL-C during pregnancy and postpartum.These abnormalities of lipid metabolism during pregnancy and postpartum might have an effect on development of diseases such as atherosclerosis. The detailed studies of lipid metabolism accompanied by pregnancy may be required.
- 一般社団法人 国立医療学会の論文
一般社団法人 国立医療学会 | 論文
- An evaluation of interferon .ALPHA. in a few diseases during childhood.
- A Case of the Meckel's Diverticulum
- Studies on respiratory failure in pulmonary tuberculosis. (The second report). Exercise test.:-Exercise Test-
- The total lung function in bronchial asthma. 2. The lung function in steroid dependent bronchial asthma.:2. THE LUNG FUNCTION IN STEROID DEPENDENT BRONCHIAL ASTHMA
- 2. CURRENT STATE OF DIALYSIS MEDICAL CARE IN JAPAN: DIALYSIS THERAPY IN JAPAN: AN OVERVIEW