Malignant Lymphoma with Cytomegalovirus Infection:—An Adult Autopsy Case—

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We reported an autopsy case of 56-years-old male showing malignant lymphoma arising from peripyloric lymph node (lymphoblastic type) with cytomegalovirus infection. The viral infection was seen in the lungs, stomach and adrenal glands. The lung was heavy weighing 795 gm, in right and 355 gm, in left. There was no prominent interstitial pneumonia but the cytomegalovirus infection was prominent with hyaline membrane like disease. The stomach and duodenum showed numerous shallow ulcers and the cytomegalovirus infected cells were seen not only near the ulcers but in normal looking mucosa. Many infected cells were in the bottom of the gastric glands. The adrenal glands showed numerous necrotic foci surrounded by cytomegalovirus infected cells in the cortex.We discussed the majority cases of the cytomegalovirus infection as seen in the immunosuppresive conditions and the possibility that the lymphocyte activity might have the most important role in these cases.We discussed also, the fact that these cases are increasing in number, recently and various clinical manifestations are being reported in the cytomegalovirus infection.
一般社団法人国立医療学会の論文