Functianal and Biapsy Study of the Liver
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概要
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We carried out a histologic examination of the biopsy material of the liver obtained during upper abdominal operation. We had 60 cases in all. 44 cases of them were suffering from such digestive disorder as cancer, ulcer, gastritis, 12 cases from gall bladder stone and 4 cases from liver disease. 28 of 60 cases received blood transfusion before the operation.We investigated a correlation between histopathologic findings of the liver and biochemical tests of the serum and also some influence of blood transfusion upon serum transaminase activity.The results are as follows:1. Relation between serum glutamic oxaloacetic, glutamic pyruvic transaminase activity and liver cell: 18 of 35 cases whose transaminase activity was in the normal range had no histologic change of the liver cells, but the other 17 had various sorts of hepatocellular degeneration or necrosis. 6 of 8 cases whose transaminase activity was high had change of the cells, but 2 had no change. 44.2% of the result did not come up as we had expected.2. Relation between serum globulin and cell-infiltration in the Glisson's capsule: 28 of 33 cases whose serum albumin-globulin ratio was normal had no cell-infiltration into Glisson's, capsule, but 5 had infiltration. 11 of 27 cases whose ratio was low had infiltration, but 16 had no infiltration. Close to half of the latter had hypoproteinemia and also hypoalbuminemia without liver injury.3. We found 13 cases whose serum transaminase activity was normal by the time of the biopsy and rised after that time. 11 cases had blood transfusion before biopsy. 2 of 11 cases had no histopathologic change in the liver, but 9 had some change. Some may be early stage of serum hepatitis and the others are liver injury having no connection with serum hepatitis.We think that they seem to have the tendency to contract serum hepatitis when they have any existing injury of the liver.
- 一般社団法人 国立医療学会の論文
一般社団法人 国立医療学会 | 論文
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