The Connection between Donor Blood Transfusion and Past-transfusion Hepatitis

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The amount of donor blood was occupied 60.2% of the whole amount of blood supply in Hokkaido in 1965.The incidence of post-transfusion hepatitis after donor blood transfusion had been generally lower than that of non-donative (commercial based) blood transfusion, but year after year it has been becoming higher for recent few years, and reached to approximately 6% in 1965.From this viewpoint, the connection was studied between post-transfusion hepatitis and donor's sex, age, occupation, and frequency of blood offer, level of blood specific gravity, blood type, value of serum transaminase and fraction of serum protein, etc., but nothing was found in this point.In order to avoid post-transfusion hepatitis, pulmonary resection without blood trans-fusion was performed on 60 cases for the past three years in Asahigawa National Sanatorium. In this case, hepaitis never occured, but liver dysfunctions that were supposed to be occured by the influence of anesthesia and surgical damge were temporarily observed in two weeks after operation.By abministering proper amount of plasma expander and iron agents without blood transfusion, there was no difference of prognosis between such cases and those after blood transfusion.As a conclusion, for prevention of post-transfusion hepatitis, it is essential to avoid the misuse of blood transfusion and to give the reasonable amount, even if the blood is donative.
一般社団法人国立医療学会の論文