Human Health Risk Assessment of Di(2-ethylhexyl)phthalate
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概要
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Di(2-ethylhexyl)phthalate (DEHP) is predominantly used as a plasticizes in flexible polyvinyl chloride (PVC). DEHP is emitted to the environment during the production of PVC products, during their use and after disposal. Hazard and risk of DEHP have been assessed in varying degrees by both domestically and abroad, however, human health risk to general population has not been sufficiently evaluated in Japan. In this study, the distributions of age-specific and gender-specific daily intakes of DEHP via indoor/outdoor air, diet, baby formula and baby food were estimated. Furthermore, the human health risks of DEHP were evaluated based on testicular and reproductive toxicity data. The results of the daily intake estimations indicate that the 1-year-old child showed the largest amount of DEHP daily intake among all the age-specific groups and its major pathway was estimated to be the food intake. The estimated risk levels of DEHP to the testicular and reproductive endpoints were judged to be of no particular concern for all the age groups in Japan.
- 社団法人 環境科学会の論文
社団法人 環境科学会 | 論文
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