Effects of Concomitant Bupivacaine and Infusion Volume on the Analgesic Effect of Epidural Fentanyl After Lower Abdominal Surgery

スポンサーリンク

概要

• 論文の詳細を見る

• We examined the effects of bupivacaine added to epidural fentanyl and a difference in the volume of fentanyl solution alone on postoperative pain relief in patients who had undergone lower abdominal surgery, and a difference in the volume of solution in the case of fentanyl alone.Method: Sixty-eight patients received O2, nitrous oxide, sevoflurane and epidural local anesthetics during surgery, and epidural injection of fentanyl 50μg with saline 4ml at the end of surgery. The patients were allocated to three groups and fentanyl 20μg/h was given together with the following: Group B, 0.2% bupivacaine 2ml/h; Group S2, saline 2ml/h; Group S0.5, saline 0.5ml/h. We recorded the analgesic scores and side effects 0, 2, 6, 12, 18, 24 and 48h after surgery.Results: There were no significant differences in the analgesic score or the frequency of requests for supplemental analgesics between group B and group S2. The analgesic score in the group S0.5 was significantly lower than that in the group B and group S2 (p<0.05). Two patients (9%) in the group B complained of lower limb numbness after 6hour operation. Neither severe hypotension nor severe respiratory depression was observed in any patient, but somnolence was revealed in about 20% patients.Conclusion: Addition of 0.2% bupivacaine to epidural fentanyl 20μg/h had no advantageous effect on postoperative analgesia. Analgesic effect of epidural fentanyl in 2ml/h was significantly stronger than that of fentanyl in 0.5ml/h.

• 一般社団法人 日本ペインクリニック学会の論文

一般社団法人 日本ペインクリニック学会 | 論文

• 神経障害性疼痛の症状から予測するガバペンチンの鎮痛効果
• 腰部硬膜外穿刺における各種画像検査による距離の予測
• くも膜下モルヒネに高用量のブピバカインを併用し良好な鎮痛が得られた2 症例
• 尖圭コンジローマ外科的切除時の痛み緩和目的でのリドカインテープ(ペンレス^【○!R】)使用経験
• 特発性脳脊髄液漏出症に対する経椎間孔的硬膜外自家血パッチの経験

もっと見る

スポンサーリンク