The effect of supplementary administration of morphine hydrochloride to spinal anesthesia on tenesmus after transuethral resection of the prostate (TUR-P)

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We examined the effect of supplementary administration of morphine hydrochloride to spinal anesthesia on the tenesmus after transurethral resection of the prostate. Forty-four patients were divided into a control group (n=20) and a morphine group (n=24). In the control group, 2.5 or 3ml of dibucaine hydrochloride was administered to the spinal subarachnoidal space through a Quincke Badcock type spinal needle inserted between L3/L4 or L4//L5. In the morphine group, 0.1mg morphine hydrochloride injected into the 2.5 or 3ml dibucaine hydrochloride was given to cerebrospinal fluid with the spinal needle. The tenesmus was significantly relieved for 24 hours following operation in the morphine group compared to the control group (P=0.039), and the required amount of NSAIDs suppository per patient body weight was significantly decreased in the morphine group (P=0.034). No adverse effects except skin itchiness and constipation were observed. Compared with other anesthetic means such as epidural anesthesia, supplementary administration of morphine hydrochloride to spinal anesthesia was easy to achieve and very effective on the tenesmus after transurethral resection of the prostate.
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